Difference between revisions of "YKL004W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001487 YKL004W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''AUR1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''AUR1 '' | ||
Latest revision as of 07:45, 23 January 2012
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| Systematic name | YKL004W |
| Gene name | AUR1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XI:435580..436785 |
| Primary SGDID | S000001487 |
Description of YKL004W: Phosphatidylinositol:ceramide phosphoinositol transferase (IPC synthase), required for sphingolipid synthesis; can mutate to confer aureobasidin A resistance[1][2]
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Contents
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References
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- Jump up ↑ Heidler SA and Radding JA (1995) The AUR1 gene in Saccharomyces cerevisiae encodes dominant resistance to the antifungal agent aureobasidin A (LY295337). Antimicrob Agents Chemother 39(12):2765-9 SGD PMID 8593016
- Jump up ↑ Nagiec MM, et al. (1997) Sphingolipid synthesis as a target for antifungal drugs. Complementation of the inositol phosphorylceramide synthase defect in a mutant strain of Saccharomyces cerevisiae by the AUR1 gene. J Biol Chem 272(15):9809-17 SGD PMID 9092515
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