Difference between revisions of "YIL046W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YIL046W YIL046W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001308 YIL046W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''MET30 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''MET30 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr IX:268650..270572
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|nowrap| Chr IX:268651..270573
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000001308
 
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'''Description of {{PAGENAME}}:''' F-box protein containing five copies of the WD40 motif, controls cell cycle function, sulfur metabolism, and methionine biosynthesis as part of the ubiquitin ligase complex; interacts with and regulates Met4p, localizes within the nucleus<ref name='S000059458'>Smothers DB, et al. (2000) The abundance of Met30p limits SCF(Met30p) complex activity and is regulated by methionine availability. Mol Cell Biol 20(21):7845-52 {{SGDpaper|S000059458}} PMID 11027256</ref><ref name='S000042750'>Rouillon A, et al. (2000) Feedback-regulated degradation of the transcriptional activator Met4 is triggered by the SCF(Met30 )complex. EMBO J 19(2):282-94
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'''Description of YIL046W:''' F-box protein containing five copies of the WD40 motif, controls cell cycle function, sulfur metabolism, and methionine biosynthesis as part of the ubiquitin ligase complex; interacts with and regulates Met4p, localizes within the nucleus<ref name='S000042750'>Rouillon A, et al. (2000) Feedback-regulated degradation of the transcriptional activator Met4 is triggered by the SCF(Met30 )complex. EMBO J 19(2):282-94 {{SGDpaper|S000042750}} PMID 10637232</ref><ref name='S000059458'>Smothers DB, et al. (2000) The abundance of Met30p limits SCF(Met30p) complex activity and is regulated by methionine availability. Mol Cell Biol 20(21):7845-52
  {{SGDpaper|S000042750}} PMID 10637232</ref>
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  {{SGDpaper|S000059458}} PMID 11027256</ref>
 
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<!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation -->
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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Latest revision as of 06:45, 23 January 2012

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Systematic name YIL046W
Gene name MET30
Aliases ZRG11
Feature type ORF, Verified
Coordinates Chr IX:268651..270573
Primary SGDID S000001308


Description of YIL046W: F-box protein containing five copies of the WD40 motif, controls cell cycle function, sulfur metabolism, and methionine biosynthesis as part of the ubiquitin ligase complex; interacts with and regulates Met4p, localizes within the nucleus[1][2]




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Community Commentary

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Interactions

Other Interactions

Other Topic: NOT Regulatory Other Interactions interaction with SWE1
Despite previous reports to the contrary, Met30p is not required for Swe1p degradation [3] [4]





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References

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  1. Rouillon A, et al. (2000) Feedback-regulated degradation of the transcriptional activator Met4 is triggered by the SCF(Met30 )complex. EMBO J 19(2):282-94 SGD PMID 10637232
  2. Smothers DB, et al. (2000) The abundance of Met30p limits SCF(Met30p) complex activity and is regulated by methionine availability. Mol Cell Biol 20(21):7845-52 SGD PMID 11027256
  3. McMillan JN, et al. (2002) Determinants of Swe1p degradation in Saccharomyces cerevisiae. Mol Biol Cell 13(10):3560-75 SGD PMID 12388757
  4. submitted by Daniel Lew on 2003-03-03

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