Difference between revisions of "YIL008W"
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− | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001270 YIL008W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''URM1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''URM1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
− | |nowrap| Chr IX: | + | |nowrap| Chr IX:342536..342835 |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000001270 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000001270 | ||
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− | '''Description of YIL008W:''' Ubiquitin-like protein | + | '''Description of YIL008W:''' Ubiquitin-like protein involved in thiolation of cytoplasmic tRNAs; receives sulfur from the E1-like enzyme Uba4p and transfers it to tRNA; also functions as a protein tag with roles in nutrient sensing and oxidative stress response<ref name='S000051101'>Furukawa K, et al. (2000) A protein conjugation system in yeast with homology to biosynthetic enzyme reaction of prokaryotes. J Biol Chem 275(11):7462-5 {{SGDpaper|S000051101}} PMID 10713047</ref><ref name='S000075061'>Goehring AS, et al. (2003) Urmylation: a ubiquitin-like pathway that functions during invasive growth and budding in yeast. Mol Biol Cell 14(11):4329-41 {{SGDpaper|S000075061}} PMID 14551258</ref><ref name='S000130718'>Leidel S, et al. (2009) Ubiquitin-related modifier Urm1 acts as a sulphur carrier in thiolation of eukaryotic transfer RNA. Nature 458(7235):228-32 {{SGDpaper|S000130718}} PMID 19145231</ref><ref name='S000128990'>Noma A, et al. (2009) Mechanistic characterization of the sulfur-relay system for eukaryotic 2-thiouridine biogenesis at tRNA wobble positions. Nucleic Acids Res 37(4):1335-52 |
− | {{SGDpaper| | + | {{SGDpaper|S000128990}} PMID 19151091</ref> |
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Latest revision as of 07:45, 23 January 2012
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Systematic name | YIL008W |
Gene name | URM1 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr IX:342536..342835 |
Primary SGDID | S000001270 |
Description of YIL008W: Ubiquitin-like protein involved in thiolation of cytoplasmic tRNAs; receives sulfur from the E1-like enzyme Uba4p and transfers it to tRNA; also functions as a protein tag with roles in nutrient sensing and oxidative stress response[1][2][3][4]
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References
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- ↑ Furukawa K, et al. (2000) A protein conjugation system in yeast with homology to biosynthetic enzyme reaction of prokaryotes. J Biol Chem 275(11):7462-5 SGD PMID 10713047
- ↑ Goehring AS, et al. (2003) Urmylation: a ubiquitin-like pathway that functions during invasive growth and budding in yeast. Mol Biol Cell 14(11):4329-41 SGD PMID 14551258
- ↑ Leidel S, et al. (2009) Ubiquitin-related modifier Urm1 acts as a sulphur carrier in thiolation of eukaryotic transfer RNA. Nature 458(7235):228-32 SGD PMID 19145231
- ↑ Noma A, et al. (2009) Mechanistic characterization of the sulfur-relay system for eukaryotic 2-thiouridine biogenesis at tRNA wobble positions. Nucleic Acids Res 37(4):1335-52 SGD PMID 19151091
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