Difference between revisions of "YHR178W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001221 YHR178W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''STB5 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''STB5 '' | ||
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| − | '''Description of YHR178W:''' | + | '''Description of YHR178W:''' Transcription factor, involved in regulating multidrug resistance and oxidative stress response; forms a heterodimer with Pdr1p; contains a Zn(II)2Cys6 zinc finger domain that interacts with a pleiotropic drug resistance element in vitro<ref name='S000076583'>Akache B, et al. (2004) Complex interplay among regulators of drug resistance genes in Saccharomyces cerevisiae. J Biol Chem 279(27):27855-60 {{SGDpaper|S000076583}} PMID 15123673</ref><ref name='S000054148'>Kasten MM and Stillman DJ (1997) Identification of the Saccharomyces cerevisiae genes STB1-STB5 encoding Sin3p binding proteins. Mol Gen Genet 256(4):376-86 {{SGDpaper|S000054148}} PMID 9393435</ref><ref name='S000117952'>Larochelle M, et al. (2006) Oxidative stress-activated zinc cluster protein Stb5 has dual activator/repressor functions required for pentose phosphate pathway regulation and NADPH production. Mol Cell Biol 26(17):6690-701 |
| − | {{SGDpaper| | + | {{SGDpaper|S000117952}} PMID 16914749</ref> |
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Latest revision as of 06:45, 23 January 2012
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| Systematic name | YHR178W |
| Gene name | STB5 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr VIII:459299..461530 |
| Primary SGDID | S000001221 |
Description of YHR178W: Transcription factor, involved in regulating multidrug resistance and oxidative stress response; forms a heterodimer with Pdr1p; contains a Zn(II)2Cys6 zinc finger domain that interacts with a pleiotropic drug resistance element in vitro[1][2][3]
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References
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- ↑ Akache B, et al. (2004) Complex interplay among regulators of drug resistance genes in Saccharomyces cerevisiae. J Biol Chem 279(27):27855-60 SGD PMID 15123673
- ↑ Kasten MM and Stillman DJ (1997) Identification of the Saccharomyces cerevisiae genes STB1-STB5 encoding Sin3p binding proteins. Mol Gen Genet 256(4):376-86 SGD PMID 9393435
- ↑ Larochelle M, et al. (2006) Oxidative stress-activated zinc cluster protein Stb5 has dual activator/repressor functions required for pentose phosphate pathway regulation and NADPH production. Mol Cell Biol 26(17):6690-701 SGD PMID 16914749
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