Difference between revisions of "YHR171W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001214 YHR171W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001214 YHR171W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''ATG7 ''
 
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'''Description of YHR171W:''' Autophagy-related protein and dual specificity member of the E1 family of ubiquitin-activating enzymes; mediates the conjugation of Atg12p with Atg5p and Atg8p with phosphatidylethanolamine, required steps in autophagosome formation<ref name='S000077450'>Ichimura Y, et al. (2004) In vivo and in vitro reconstitution of Atg8 conjugation essential for autophagy. J Biol Chem 279(39):40584-92 {{SGDpaper|S000077450}} PMID 15277523</ref><ref name='S000059720'>Ichimura Y, et al. (2000) A ubiquitin-like system mediates protein lipidation. Nature 408(6811):488-92 {{SGDpaper|S000059720}} PMID 11100732</ref><ref name='S000051835'>Tsukada M and Ohsumi Y (1993) Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae. FEBS Lett 333(1-2):169-74 {{SGDpaper|S000051835}} PMID 8224160</ref><ref name='S000039962'>Mizushima N, et al. (1998) A protein conjugation system essential for autophagy. Nature 395(6700):395-8
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'''Description of YHR171W:''' Autophagy-related protein and dual specificity member of the E1 family of ubiquitin-activating enzymes; mediates the conjugation of Atg12p with Atg5p and Atg8p with phosphatidylethanolamine, required steps in autophagosome formation<ref name='S000059720'>Ichimura Y, et al. (2000) A ubiquitin-like system mediates protein lipidation. Nature 408(6811):488-92 {{SGDpaper|S000059720}} PMID 11100732</ref><ref name='S000077450'>Ichimura Y, et al. (2004) In vivo and in vitro reconstitution of Atg8 conjugation essential for autophagy. J Biol Chem 279(39):40584-92 {{SGDpaper|S000077450}} PMID 15277523</ref><ref name='S000039962'>Mizushima N, et al. (1998) A protein conjugation system essential for autophagy. Nature 395(6700):395-8 {{SGDpaper|S000039962}} PMID 9759731</ref><ref name='S000051835'>Tsukada M and Ohsumi Y (1993) Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae. FEBS Lett 333(1-2):169-74
{{SGDpaper|S000039962}} PMID 9759731</ref>
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{{SGDpaper|S000051835}} PMID 8224160</ref>
 
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Latest revision as of 06:45, 23 January 2012

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Systematic name YHR171W
Gene name ATG7
Aliases APG11, APG7, CVT2
Feature type ORF, Verified
Coordinates Chr VIII:445713..447605
Primary SGDID S000001214


Description of YHR171W: Autophagy-related protein and dual specificity member of the E1 family of ubiquitin-activating enzymes; mediates the conjugation of Atg12p with Atg5p and Atg8p with phosphatidylethanolamine, required steps in autophagosome formation[1][2][3][4]




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References

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  1. Ichimura Y, et al. (2000) A ubiquitin-like system mediates protein lipidation. Nature 408(6811):488-92 SGD PMID 11100732
  2. Ichimura Y, et al. (2004) In vivo and in vitro reconstitution of Atg8 conjugation essential for autophagy. J Biol Chem 279(39):40584-92 SGD PMID 15277523
  3. Mizushima N, et al. (1998) A protein conjugation system essential for autophagy. Nature 395(6700):395-8 SGD PMID 9759731
  4. Tsukada M and Ohsumi Y (1993) Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae. FEBS Lett 333(1-2):169-74 SGD PMID 8224160

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