Difference between revisions of "YHR100C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001142 YHR100C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''GEP4 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''GEP4 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr VIII: | + | |nowrap| Chr VIII:314673..314116 |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000001142 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000001142 | ||
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| − | '''Description of YHR100C:''' | + | '''Description of YHR100C:''' Mitochondrial phosphatidylglycerophosphatase (PGP phosphatase), dephosphorylates phosphatidylglycerolphosphate to generate phosphatidylglycerol, an essential step during cardiolipin biosynthesis; null mutant is sensitive to tunicamycin, DTT<ref name='S000129376'>Osman C, et al. (2009) The genetic interactome of prohibitins: coordinated control of cardiolipin and phosphatidylethanolamine by conserved regulators in mitochondria. J Cell Biol 184(4):583-96 {{SGDpaper|S000129376}} PMID 19221197</ref><ref name='S000134639'>Osman C, et al. (2010) A mitochondrial phosphatase required for cardiolipin biosynthesis: the PGP phosphatase Gep4. EMBO J 29(12):1976-87 |
| − | {{SGDpaper| | + | {{SGDpaper|S000134639}} PMID 20485265</ref> |
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Latest revision as of 06:45, 23 January 2012
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| Systematic name | YHR100C |
| Gene name | GEP4 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr VIII:314673..314116 |
| Primary SGDID | S000001142 |
Description of YHR100C: Mitochondrial phosphatidylglycerophosphatase (PGP phosphatase), dephosphorylates phosphatidylglycerolphosphate to generate phosphatidylglycerol, an essential step during cardiolipin biosynthesis; null mutant is sensitive to tunicamycin, DTT[1][2]
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References
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- ↑ Osman C, et al. (2009) The genetic interactome of prohibitins: coordinated control of cardiolipin and phosphatidylethanolamine by conserved regulators in mitochondria. J Cell Biol 184(4):583-96 SGD PMID 19221197
- ↑ Osman C, et al. (2010) A mitochondrial phosphatase required for cardiolipin biosynthesis: the PGP phosphatase Gep4. EMBO J 29(12):1976-87 SGD PMID 20485265
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