Difference between revisions of "YHR068W"
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− | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001110 YHR068W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''DYS1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''DYS1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
− | |nowrap| Chr VIII: | + | |nowrap| Chr VIII:232133..233296 |
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− | | | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000001110 |
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− | '''Description of | + | '''Description of YHR068W:''' Deoxyhypusine synthase, catalyzes formation of deoxyhypusine, the first step in hypusine biosynthesis; triggers posttranslational hypusination of translation elongation factor eIF-5A and regulates its intracellular levels; tetrameric<ref name='S000046348'>Abid R, et al. (1997) Novel features of the functional site and expression of the yeast deoxyhypusine synthase. Biol Signals 6(3):157-65 {{SGDpaper|S000046348}} PMID 9285099</ref><ref name='S000039694'>Kang KR, et al. (1995) Identification of YHR068w in Saccharomyces cerevisiae chromosome VIII as a gene for deoxyhypusine synthase. Expression and characterization of the enzyme. J Biol Chem 270(31):18408-12 {{SGDpaper|S000039694}} PMID 7629166</ref><ref name='S000075161'>Thompson GM, et al. (2003) Mapping eIF5A binding sites for Dys1 and Lia1: in vivo evidence for regulation of eIF5A hypusination. FEBS Lett 555(3):464-8 |
− | {{SGDpaper| | + | {{SGDpaper|S000075161}} PMID 14675757</ref> |
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==Community Commentary== | ==Community Commentary== | ||
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+ | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
+ | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
+ | J Biol Chem 278(5):3265-74</ref> | ||
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==References== | ==References== | ||
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Latest revision as of 06:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
Systematic name | YHR068W |
Gene name | DYS1 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr VIII:232133..233296 |
Primary SGDID | S000001110 |
Description of YHR068W: Deoxyhypusine synthase, catalyzes formation of deoxyhypusine, the first step in hypusine biosynthesis; triggers posttranslational hypusination of translation elongation factor eIF-5A and regulates its intracellular levels; tetrameric[1][2][3]
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References
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- ↑ Abid R, et al. (1997) Novel features of the functional site and expression of the yeast deoxyhypusine synthase. Biol Signals 6(3):157-65 SGD PMID 9285099
- ↑ Kang KR, et al. (1995) Identification of YHR068w in Saccharomyces cerevisiae chromosome VIII as a gene for deoxyhypusine synthase. Expression and characterization of the enzyme. J Biol Chem 270(31):18408-12 SGD PMID 7629166
- ↑ Thompson GM, et al. (2003) Mapping eIF5A binding sites for Dys1 and Lia1: in vivo evidence for regulation of eIF5A hypusination. FEBS Lett 555(3):464-8 SGD PMID 14675757
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