Difference between revisions of "YER173W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YER173W YER173W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000975 YER173W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''RAD24 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''RAD24 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr V:536295..538274
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|nowrap| Chr V:536300..538279
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000000975
 
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'''Description of {{PAGENAME}}:''' Checkpoint protein, involved in the activation of the DNA damage and meiotic pachytene checkpoints; subunit of a clamp loader that loads Rad17p-Mec3p-Ddc1p onto DNA; homolog of human and S. pombe Rad17 protein<ref name='S000073739'>Shinohara M, et al. (2003) The mitotic DNA damage checkpoint proteins Rad17 and Rad24 are required for repair of double-strand breaks during meiosis in yeast. Genetics 164(3):855-65 {{SGDpaper|S000073739}} PMID 12871899</ref><ref name='S000072671'>Majka J and Burgers PM (2003) Yeast Rad17/Mec3/Ddc1: a sliding clamp for the DNA damage checkpoint. Proc Natl Acad Sci U S A 100(5):2249-54 {{SGDpaper|S000072671}} PMID 12604797</ref><ref name='S000053765'>Lydall D, et al. (1996) A meiotic recombination checkpoint controlled by mitotic checkpoint genes. Nature 383(6603):840-3
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'''Description of YER173W:''' Checkpoint protein, involved in the activation of the DNA damage and meiotic pachytene checkpoints; subunit of a clamp loader that loads Rad17p-Mec3p-Ddc1p onto DNA; homolog of human and S. pombe Rad17 protein<ref name='S000053765'>Lydall D, et al. (1996) A meiotic recombination checkpoint controlled by mitotic checkpoint genes. Nature 383(6603):840-3 {{SGDpaper|S000053765}} PMID 8893012</ref><ref name='S000072671'>Majka J and Burgers PM (2003) Yeast Rad17/Mec3/Ddc1: a sliding clamp for the DNA damage checkpoint. Proc Natl Acad Sci U S A 100(5):2249-54 {{SGDpaper|S000072671}} PMID 12604797</ref><ref name='S000073739'>Shinohara M, et al. (2003) The mitotic DNA damage checkpoint proteins Rad17 and Rad24 are required for repair of double-strand breaks during meiosis in yeast. Genetics 164(3):855-65
  {{SGDpaper|S000053765}} PMID 8893012</ref>
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  {{SGDpaper|S000073739}} PMID 12871899</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YER173W
Gene name RAD24
Aliases RS1
Feature type ORF, Verified
Coordinates Chr V:536300..538279
Primary SGDID S000000975


Description of YER173W: Checkpoint protein, involved in the activation of the DNA damage and meiotic pachytene checkpoints; subunit of a clamp loader that loads Rad17p-Mec3p-Ddc1p onto DNA; homolog of human and S. pombe Rad17 protein[1][2][3]




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References

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  1. Lydall D, et al. (1996) A meiotic recombination checkpoint controlled by mitotic checkpoint genes. Nature 383(6603):840-3 SGD PMID 8893012
  2. Majka J and Burgers PM (2003) Yeast Rad17/Mec3/Ddc1: a sliding clamp for the DNA damage checkpoint. Proc Natl Acad Sci U S A 100(5):2249-54 SGD PMID 12604797
  3. Shinohara M, et al. (2003) The mitotic DNA damage checkpoint proteins Rad17 and Rad24 are required for repair of double-strand breaks during meiosis in yeast. Genetics 164(3):855-65 SGD PMID 12871899

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