Difference between revisions of "YER118C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000920 YER118C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000920 YER118C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''SHO1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''SHO1 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr V:399051..397948
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|nowrap| Chr V:399055..397952
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000000920
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000000920
 
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'''Description of YER118C:''' Transmembrane osmosensor, participates in activation of both the Cdc42p- and MAP kinase-dependent filamentous growth pathway and the high-osmolarity glycerol response pathway<ref name='S000077085'>Cullen PJ, et al. (2004) A signaling mucin at the head of the Cdc42- and MAPK-dependent filamentous growth pathway in yeast. Genes Dev 18(14):1695-708 {{SGDpaper|S000077085}} PMID 15256499</ref><ref name='S000075513'>O'Rourke SM and Herskowitz I (2004) Unique and redundant roles for HOG MAPK pathway components as revealed by whole-genome expression analysis. Mol Biol Cell 15(2):532-42 {{SGDpaper|S000075513}} PMID 14595107</ref><ref name='S000049858'>Posas F and Saito H (1997) Osmotic activation of the HOG MAPK pathway via Ste11p MAPKKK: scaffold role of Pbs2p MAPKK. Science 276(5319):1702-5
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'''Description of YER118C:''' Transmembrane osmosensor involved in activation of the Cdc42p- and MAP kinase-dependent filamentous growth pathway and the high-osmolarity glycerol response pathway; phosphorylated by Hog1p; interacts with Pbs2p, Msb2p, Hkr1p, and Ste11p<ref name='S000077085'>Cullen PJ, et al. (2004) A signaling mucin at the head of the Cdc42- and MAPK-dependent filamentous growth pathway in yeast. Genes Dev 18(14):1695-708 {{SGDpaper|S000077085}} PMID 15256499</ref><ref name='S000121379'>Hao N, et al. (2007) A systems-biology analysis of feedback inhibition in the Sho1 osmotic-stress-response pathway. Curr Biol 17(8):659-67 {{SGDpaper|S000121379}} PMID 17363249</ref><ref name='S000075513'>O'Rourke SM and Herskowitz I (2004) Unique and redundant roles for HOG MAPK pathway components as revealed by whole-genome expression analysis. Mol Biol Cell 15(2):532-42 {{SGDpaper|S000075513}} PMID 14595107</ref><ref name='S000049858'>Posas F and Saito H (1997) Osmotic activation of the HOG MAPK pathway via Ste11p MAPKKK: scaffold role of Pbs2p MAPKK. Science 276(5319):1702-5 {{SGDpaper|S000049858}} PMID 9180081</ref><ref name='S000116674'>Tatebayashi K, et al. (2006) Adaptor functions of Cdc42, Ste50, and Sho1 in the yeast osmoregulatory HOG MAPK pathway. EMBO J 25(13):3033-44 {{SGDpaper|S000116674}} PMID 16778768</ref><ref name='S000123317'>Tatebayashi K, et al. (2007) Transmembrane mucins Hkr1 and Msb2 are putative osmosensors in the SHO1 branch of yeast HOG pathway. EMBO J 26(15):3521-33 {{SGDpaper|S000123317}} PMID 17627274</ref><ref name='S000075316'>Zarrinpar A, et al. (2003) Optimization of specificity in a cellular protein interaction network by negative selection. Nature 426(6967):676-80
  {{SGDpaper|S000049858}} PMID 9180081</ref>
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  {{SGDpaper|S000075316}} PMID 14668868</ref>
 
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Latest revision as of 06:45, 23 January 2012

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Systematic name YER118C
Gene name SHO1
Aliases SSU81
Feature type ORF, Verified
Coordinates Chr V:399055..397952
Primary SGDID S000000920


Description of YER118C: Transmembrane osmosensor involved in activation of the Cdc42p- and MAP kinase-dependent filamentous growth pathway and the high-osmolarity glycerol response pathway; phosphorylated by Hog1p; interacts with Pbs2p, Msb2p, Hkr1p, and Ste11p[1][2][3][4][5][6][7]




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References

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  1. Cullen PJ, et al. (2004) A signaling mucin at the head of the Cdc42- and MAPK-dependent filamentous growth pathway in yeast. Genes Dev 18(14):1695-708 SGD PMID 15256499
  2. Hao N, et al. (2007) A systems-biology analysis of feedback inhibition in the Sho1 osmotic-stress-response pathway. Curr Biol 17(8):659-67 SGD PMID 17363249
  3. O'Rourke SM and Herskowitz I (2004) Unique and redundant roles for HOG MAPK pathway components as revealed by whole-genome expression analysis. Mol Biol Cell 15(2):532-42 SGD PMID 14595107
  4. Posas F and Saito H (1997) Osmotic activation of the HOG MAPK pathway via Ste11p MAPKKK: scaffold role of Pbs2p MAPKK. Science 276(5319):1702-5 SGD PMID 9180081
  5. Tatebayashi K, et al. (2006) Adaptor functions of Cdc42, Ste50, and Sho1 in the yeast osmoregulatory HOG MAPK pathway. EMBO J 25(13):3033-44 SGD PMID 16778768
  6. Tatebayashi K, et al. (2007) Transmembrane mucins Hkr1 and Msb2 are putative osmosensors in the SHO1 branch of yeast HOG pathway. EMBO J 26(15):3521-33 SGD PMID 17627274
  7. Zarrinpar A, et al. (2003) Optimization of specificity in a cellular protein interaction network by negative selection. Nature 426(6967):676-80 SGD PMID 14668868

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