Difference between revisions of "YBR295W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000499 YBR295W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''PCA1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''PCA1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr II: | + | |nowrap| Chr II:792849..796499 |
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| − | | | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000000499 |
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| − | '''Description of | + | '''Description of YBR295W:''' Cadmium transporting P-type ATPase; may also have a role in copper and iron homeostasis; stabilized by Cd binding, which prevents ubiquitination; S288C and other lab strains contain a G970R mutation which eliminates Cd transport function<ref name='S000127525'>Adle DJ and Lee J (2008) Expressional Control of a Cadmium-transporting P1B-type ATPase by a Metal Sensing Degradation Signal. J Biol Chem 283(46):31460-8 {{SGDpaper|S000127525}} PMID 18753133</ref><ref name='S000119644'>Adle DJ, et al. (2007) A cadmium-transporting P1B-type ATPase in yeast Saccharomyces cerevisiae. J Biol Chem 282(2):947-55 {{SGDpaper|S000119644}} PMID 17107946</ref><ref name='S000074663'>De Freitas JM, et al. (2004) Exploratory and confirmatory gene expression profiling of mac1Delta. J Biol Chem 279(6):4450-8 {{SGDpaper|S000074663}} PMID 14534306</ref><ref name='S000049758'>Rad MR, et al. (1994) A putative P-type Cu(2+)-transporting ATPase gene on chromosome II of Saccharomyces cerevisiae. Yeast 10(9):1217-25 {{SGDpaper|S000049758}} PMID 7754711</ref><ref name='S000046593'>Shiraishi E, et al. (2000) The cadmium-resistant gene, CAD2, which is a mutated putative copper-transporter gene (PCA1), controls the intracellular cadmium-level in the yeast S. cerevisiae. Curr Genet 37(2):79-86 |
{{SGDpaper|S000046593}} PMID 10743563</ref> | {{SGDpaper|S000046593}} PMID 10743563</ref> | ||
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==Community Commentary== | ==Community Commentary== | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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==References== | ==References== | ||
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Latest revision as of 06:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YBR295W |
| Gene name | PCA1 |
| Aliases | CAD2, PAY2 |
| Feature type | ORF, Verified |
| Coordinates | Chr II:792849..796499 |
| Primary SGDID | S000000499 |
Description of YBR295W: Cadmium transporting P-type ATPase; may also have a role in copper and iron homeostasis; stabilized by Cd binding, which prevents ubiquitination; S288C and other lab strains contain a G970R mutation which eliminates Cd transport function[1][2][3][4][5]
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Contents
Community Commentary
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DNA and RNA Details
Other DNA and RNA Details
Other Topic: expression
Specifically higher expression in carbon limited chemostat cultures versus carbon excess. [6] [7]
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References
See Help:References on how to add references
- ↑ Adle DJ and Lee J (2008) Expressional Control of a Cadmium-transporting P1B-type ATPase by a Metal Sensing Degradation Signal. J Biol Chem 283(46):31460-8 SGD PMID 18753133
- ↑ Adle DJ, et al. (2007) A cadmium-transporting P1B-type ATPase in yeast Saccharomyces cerevisiae. J Biol Chem 282(2):947-55 SGD PMID 17107946
- ↑ De Freitas JM, et al. (2004) Exploratory and confirmatory gene expression profiling of mac1Delta. J Biol Chem 279(6):4450-8 SGD PMID 14534306
- ↑ Rad MR, et al. (1994) A putative P-type Cu(2+)-transporting ATPase gene on chromosome II of Saccharomyces cerevisiae. Yeast 10(9):1217-25 SGD PMID 7754711
- ↑ Shiraishi E, et al. (2000) The cadmium-resistant gene, CAD2, which is a mutated putative copper-transporter gene (PCA1), controls the intracellular cadmium-level in the yeast S. cerevisiae. Curr Genet 37(2):79-86 SGD PMID 10743563
- ↑ Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
- ↑ submitted by Viktor Boer on 2003-07-25
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