Difference between revisions of "YBR215W"
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− | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000419 YBR215W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''HPC2 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''HPC2 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
− | |nowrap| Chr II: | + | |nowrap| Chr II:653356..655317 |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000000419 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000000419 | ||
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− | '''Description of YBR215W:''' | + | '''Description of YBR215W:''' Subunit of the HIR complex, a nucleosome assembly complex involved in regulation of histone gene transcription; mutants display synthetic defects with subunits of FACT, a complex that allows passage of RNA Pol II through nucleosomes<ref name='S000072261'>Formosa T, et al. (2002) Defects in SPT16 or POB3 (yFACT) in Saccharomyces cerevisiae cause dependence on the Hir/Hpc pathway: polymerase passage may degrade chromatin structure. Genetics 162(4):1557-71 {{SGDpaper|S000072261}} PMID 12524332</ref><ref name='S000087068'>Prochasson P, et al. (2005) The HIR corepressor complex binds to nucleosomes generating a distinct protein/DNA complex resistant to remodeling by SWI/SNF. Genes Dev 19(21):2534-9 {{SGDpaper|S000087068}} PMID 16264190</ref><ref name='S000039430'>Xu H, et al. (1992) Identification of a new set of cell cycle-regulatory genes that regulate S-phase transcription of histone genes in Saccharomyces cerevisiae. Mol Cell Biol 12(11):5249-59 |
{{SGDpaper|S000039430}} PMID 1406694</ref> | {{SGDpaper|S000039430}} PMID 1406694</ref> | ||
<br> | <br> |
Latest revision as of 07:45, 23 January 2012
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Systematic name | YBR215W |
Gene name | HPC2 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr II:653356..655317 |
Primary SGDID | S000000419 |
Description of YBR215W: Subunit of the HIR complex, a nucleosome assembly complex involved in regulation of histone gene transcription; mutants display synthetic defects with subunits of FACT, a complex that allows passage of RNA Pol II through nucleosomes[1][2][3]
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References
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- ↑ Formosa T, et al. (2002) Defects in SPT16 or POB3 (yFACT) in Saccharomyces cerevisiae cause dependence on the Hir/Hpc pathway: polymerase passage may degrade chromatin structure. Genetics 162(4):1557-71 SGD PMID 12524332
- ↑ Prochasson P, et al. (2005) The HIR corepressor complex binds to nucleosomes generating a distinct protein/DNA complex resistant to remodeling by SWI/SNF. Genes Dev 19(21):2534-9 SGD PMID 16264190
- ↑ Xu H, et al. (1992) Identification of a new set of cell cycle-regulatory genes that regulate S-phase transcription of histone genes in Saccharomyces cerevisiae. Mol Cell Biol 12(11):5249-59 SGD PMID 1406694
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