Difference between revisions of "YAL039C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YAL039C YAL039C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000037 YAL039C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''CYC3 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''CYC3 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr I:69526..68717
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|nowrap| Chr I:69525..68716
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000000037
 
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'''Description of {{PAGENAME}}:''' Cytochrome c heme lyase (holocytochrome c synthase), attaches heme to apo-Cyc1p in the mitochondrial intermembrane space; human ortholog may have a role in microphthalmia with linear skin defects (MLS)<ref name='S000062525'>Dumont ME, et al. (1991) Role of cytochrome c heme lyase in mitochondrial import and accumulation of cytochrome c in Saccharomyces cerevisiae. Mol Cell Biol 11(11):5487-96 {{SGDpaper|S000062525}} PMID 1656231</ref><ref name='S000039981'>Dumont ME, et al. (1987) Identification and sequence of the gene encoding cytochrome c heme lyase in the yeast Saccharomyces cerevisiae. EMBO J 6(1):235-41
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'''Description of YAL039C:''' Cytochrome c heme lyase (holocytochrome c synthase), attaches heme to apo-cytochrome c (Cyc1p or Cyc7p) in the mitochondrial intermembrane space; human ortholog may have a role in microphthalmia with linear skin defects (MLS)<ref name='S000039981'>Dumont ME, et al. (1987) Identification and sequence of the gene encoding cytochrome c heme lyase in the yeast Saccharomyces cerevisiae. EMBO J 6(1):235-41 {{SGDpaper|S000039981}} PMID 3034577</ref><ref name='S000062525'>Dumont ME, et al. (1991) Role of cytochrome c heme lyase in mitochondrial import and accumulation of cytochrome c in Saccharomyces cerevisiae. Mol Cell Biol 11(11):5487-96
  {{SGDpaper|S000039981}} PMID 3034577</ref>
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  {{SGDpaper|S000062525}} PMID 1656231</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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Anti-sense transcription on the Watson Strand opposite CYC3 has been observed in the absences of ''RRP6'' and ''XRN1''.
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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==References==
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Latest revision as of 06:45, 23 January 2012

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Systematic name YAL039C
Gene name CYC3
Aliases
Feature type ORF, Verified
Coordinates Chr I:69525..68716
Primary SGDID S000000037


Description of YAL039C: Cytochrome c heme lyase (holocytochrome c synthase), attaches heme to apo-cytochrome c (Cyc1p or Cyc7p) in the mitochondrial intermembrane space; human ortholog may have a role in microphthalmia with linear skin defects (MLS)[1][2]




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Community Commentary

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Anti-sense transcription on the Watson Strand opposite CYC3 has been observed in the absences of RRP6 and XRN1.




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References

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  1. Dumont ME, et al. (1987) Identification and sequence of the gene encoding cytochrome c heme lyase in the yeast Saccharomyces cerevisiae. EMBO J 6(1):235-41 SGD PMID 3034577
  2. Dumont ME, et al. (1991) Role of cytochrome c heme lyase in mitochondrial import and accumulation of cytochrome c in Saccharomyces cerevisiae. Mol Cell Biol 11(11):5487-96 SGD PMID 1656231

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References

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