Difference between revisions of "YAL002W"

From SGD-Wiki
Jump to: navigation, search
(Automated import of articles)
(Automated import of articles)
 
(10 intermediate revisions by 2 users not shown)
Line 4: Line 4:
 
{|{{Prettytable}} align = 'right' width = '200px'
 
{|{{Prettytable}} align = 'right' width = '200px'
 
|-
 
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YAL002W YAL002W]  
+
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000002 YAL002W]  
 
|-
 
|-
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''VPS8 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''VPS8 ''
 
|-
 
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||''FUN15, VPT8''
+
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||''FUN15, VPL8, VPT8''
 
|-
 
|-
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
 
|-
 
|-
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr I:143709..147533
+
|nowrap| Chr I:143707..147531
 +
|-
 +
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000000002
 
|}
 
|}
 
<br>
 
<br>
'''Description of {{PAGENAME}}:''' Membrane-associated hydrophilic protein that interacts with the small GTPase, Vps21p, to facilitate soluble vacuolar protein localization; required for localization and trafficking of the CPY sorting receptor; contains a RING finger motif<ref name='S000048903'>Chen YJ and Stevens TH (1996) The VPS8 gene is required for localization and trafficking of the CPY sorting receptor in Saccharomyces cerevisiae. Eur J Cell Biol 70(4):289-97 {{SGDpaper|S000048903}} PMID 8864656</ref><ref name='S000043091'>Luo W and Chang A (1997) Novel genes involved in endosomal traffic in yeast revealed by suppression of a targeting-defective plasma membrane ATPase mutant. J Cell Biol 138(4):731-46 {{SGDpaper|S000043091}} PMID 9265642</ref><ref name='S000043076'>Horazdovsky BF, et al. (1996) A novel RING finger protein, Vps8p, functionally interacts with the small GTPase, Vps21p, to facilitate soluble vacuolar protein localization. J Biol Chem 271(52):33607-15
+
'''Description of YAL002W:''' Membrane-binding component of the CORVET complex; involved in endosomal vesicle tethering and fusion in the endosome to vacuole protein targeting pathway; interacts with Vps21p; contains RING finger motif<ref name='S000048903'>Chen YJ and Stevens TH (1996) The VPS8 gene is required for localization and trafficking of the CPY sorting receptor in Saccharomyces cerevisiae. Eur J Cell Biol 70(4):289-97 {{SGDpaper|S000048903}} PMID 8864656</ref><ref name='S000043076'>Horazdovsky BF, et al. (1996) A novel RING finger protein, Vps8p, functionally interacts with the small GTPase, Vps21p, to facilitate soluble vacuolar protein localization. J Biol Chem 271(52):33607-15 {{SGDpaper|S000043076}} PMID 8969229</ref><ref name='S000043091'>Luo W and Chang A (1997) Novel genes involved in endosomal traffic in yeast revealed by suppression of a targeting-defective plasma membrane ATPase mutant. J Cell Biol 138(4):731-46 {{SGDpaper|S000043091}} PMID 9265642</ref><ref name='S000131961'>Markgraf DF, et al. (2009) The CORVET Subunit Vps8 Cooperates with the Rab5 Homolog Vps21 to Induce Clustering of Late Endosomal Compartments. Mol Biol Cell 20(24):5276-89 {{SGDpaper|S000131961}} PMID 19828734</ref><ref name='S000122612'>Peplowska K, et al. (2007) The CORVET Tethering Complex Interacts with the Yeast Rab5 Homolog Vps21 and Is Involved in Endo-Lysosomal Biogenesis. Dev Cell 12(5):739-50
  {{SGDpaper|S000043076}} PMID 8969229</ref>
+
  {{SGDpaper|S000122612}} PMID 17488625</ref>
 
<br>
 
<br>
 
<br>
 
<br>
Line 27: Line 29:
 
==Community Commentary==
 
==Community Commentary==
 
{{CommentaryHelp}}
 
{{CommentaryHelp}}
 
 
<protect>
 
  
  
Line 40: Line 39:
  
  
 
<!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation -->
 
<!--
 
Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
 
<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
 
J Biol Chem 278(5):3265-74</ref>
 
-->
 
  
 
<protect>
 
<protect>

Latest revision as of 06:45, 23 January 2012

Share your knowledge...Edit this entry! <protect>

Systematic name YAL002W
Gene name VPS8
Aliases FUN15, VPL8, VPT8
Feature type ORF, Verified
Coordinates Chr I:143707..147531
Primary SGDID S000000002


Description of YAL002W: Membrane-binding component of the CORVET complex; involved in endosomal vesicle tethering and fusion in the endosome to vacuole protein targeting pathway; interacts with Vps21p; contains RING finger motif[1][2][3][4][5]




</protect>

Community Commentary

About Community Commentary. Please share your knowledge!



<protect>

References

See Help:References on how to add references

  1. Chen YJ and Stevens TH (1996) The VPS8 gene is required for localization and trafficking of the CPY sorting receptor in Saccharomyces cerevisiae. Eur J Cell Biol 70(4):289-97 SGD PMID 8864656
  2. Horazdovsky BF, et al. (1996) A novel RING finger protein, Vps8p, functionally interacts with the small GTPase, Vps21p, to facilitate soluble vacuolar protein localization. J Biol Chem 271(52):33607-15 SGD PMID 8969229
  3. Luo W and Chang A (1997) Novel genes involved in endosomal traffic in yeast revealed by suppression of a targeting-defective plasma membrane ATPase mutant. J Cell Biol 138(4):731-46 SGD PMID 9265642
  4. Markgraf DF, et al. (2009) The CORVET Subunit Vps8 Cooperates with the Rab5 Homolog Vps21 to Induce Clustering of Late Endosomal Compartments. Mol Biol Cell 20(24):5276-89 SGD PMID 19828734
  5. Peplowska K, et al. (2007) The CORVET Tethering Complex Interacts with the Yeast Rab5 Homolog Vps21 and Is Involved in Endo-Lysosomal Biogenesis. Dev Cell 12(5):739-50 SGD PMID 17488625

See Help:Categories on how to add the wiki page for this gene to a Category </protect>