Difference between revisions of "YKR095W-A"

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'''Description of YKR095W-A:''' Component of the EKC/KEOPS protein complex with Kae1p, Gon7p, Bud32p, and Cgi121p; EKC/KEOPS complex is required for t6A tRNA modification and may have roles in telomere maintenance and transcription<ref name='S000117374'>Kisseleva-Romanova E, et al. (2006) Yeast homolog of a cancer-testis antigen defines a new transcription complex. EMBO J 25(15):3576-85 {{SGDpaper|S000117374}} PMID 16874308</ref><ref name='S000142370'>Srinivasan M, et al. (2011) The highly conserved KEOPS/EKC complex is essential for a universal tRNA modification, t6A. EMBO J 30(5):873-81
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'''Description of YKR095W-A:''' Component of the EKC/KEOPS protein complex with Kae1p, Gon7p, Bud32p, and Cgi121p; EKC/KEOPS complex is required for t6A tRNA modification and may have roles in telomere maintenance and transcription<ref name='S000147196'>Daugeron MC, et al. (2011) Gcn4 misregulation reveals a direct role for the evolutionary conserved EKC/KEOPS in the t6A modification of tRNAs. Nucleic Acids Res 39(14):6148-60 {{SGDpaper|S000147196}} PMID 21459853</ref><ref name='S000117374'>Kisseleva-Romanova E, et al. (2006) Yeast homolog of a cancer-testis antigen defines a new transcription complex. EMBO J 25(15):3576-85 {{SGDpaper|S000117374}} PMID 16874308</ref><ref name='S000142370'>Srinivasan M, et al. (2011) The highly conserved KEOPS/EKC complex is essential for a universal tRNA modification, t6A. EMBO J 30(5):873-81
 
  {{SGDpaper|S000142370}} PMID 21183954</ref>
 
  {{SGDpaper|S000142370}} PMID 21183954</ref>
 
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Revision as of 14:05, 18 November 2011

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Systematic name YKR095W-A
Gene name PCC1
Aliases
Feature type ORF, Verified
Coordinates Chr XI:625864..626205
Primary SGDID S000028512


Description of YKR095W-A: Component of the EKC/KEOPS protein complex with Kae1p, Gon7p, Bud32p, and Cgi121p; EKC/KEOPS complex is required for t6A tRNA modification and may have roles in telomere maintenance and transcription[1][2][3]




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References

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  1. Daugeron MC, et al. (2011) Gcn4 misregulation reveals a direct role for the evolutionary conserved EKC/KEOPS in the t6A modification of tRNAs. Nucleic Acids Res 39(14):6148-60 SGD PMID 21459853
  2. Kisseleva-Romanova E, et al. (2006) Yeast homolog of a cancer-testis antigen defines a new transcription complex. EMBO J 25(15):3576-85 SGD PMID 16874308
  3. Srinivasan M, et al. (2011) The highly conserved KEOPS/EKC complex is essential for a universal tRNA modification, t6A. EMBO J 30(5):873-81 SGD PMID 21183954

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