Difference between revisions of "YPR018W"

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|nowrap| Chr XVI:594473..596293
 
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==Community Commentary==
 
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==References==
 
==References==
 
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Revision as of 07:18, 30 January 2007

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Systematic name YPR018W
Gene name RLF2
Aliases CAC1
Feature type ORF, Verified
Coordinates Chr XVI:594473..596293


Description of YPR018W: Largest subunit (p90) of the Chromatin Assembly Complex (CAF-I) with Cac2p and Msi1p that assembles newly synthesized histones onto recently replicated DNA; involved in the maintenance of transcriptionally silent chromatin[1][2]




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Community Commentary

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Protein Details

Protein Modification

Modification(s): Phosphorylation

Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [3] [4]


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References

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  1. Glowczewski L, et al. (2004) Yeast chromatin assembly complex 1 protein excludes nonacetylatable forms of histone H4 from chromatin and the nucleus. Mol Cell Biol 24(23):10180-92 SGD PMID 15542829
  2. Adams CR and Kamakaka RT (1999) Chromatin assembly: biochemical identities and genetic redundancy. Curr Opin Genet Dev 9(2):185-90 SGD PMID 10322140
  3. Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
  4. submitted by Jeff Ubersax on 2004-01-29

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