Difference between revisions of "YPL128C"
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| − | '''Description of YPL128C:''' Telobox-containing general regulatory factor; binds TTAGGG repeats within subtelomeric anti-silencing regions (STARs), blocking silent chromatin propagation; binds majority of snoRNA gene promoters, required for full snoRNA expression<ref name='S000074974'>Bilaud T, et al. (1996) The telobox, a Myb-related telomeric DNA binding motif found in proteins from yeast, plants and human. Nucleic Acids Res 24(7):1294-303 {{SGDpaper|S000074974}} PMID 8614633</ref><ref name='S000053340'>Fourel G, et al. (1999) Cohabitation of insulators and silencing elements in yeast subtelomeric regions. EMBO J 18(9):2522-37 {{SGDpaper|S000053340}} PMID 10228166</ref><ref name='S000060749'>Fourel G, et al. (2001) An activation-independent role of transcription factors in insulator function. EMBO Rep 2(2):124-32 {{SGDpaper|S000060749}} PMID 11258704</ref><ref name='S000071586'>Fourel G, et al. (2002) General regulatory factors (GRFs) as genome partitioners. J Biol Chem 277(44):41736-43 {{SGDpaper|S000071586}} PMID 12200417</ref><ref name='S000040662'>Koering CE, et al. (2000) Identification of high affinity Tbf1p-binding sites within the budding yeast genome. Nucleic Acids Res 28(13):2519-26 {{SGDpaper|S000040662}} PMID 10871401</ref><ref name='S000134259'>Preti M, et al. (2010) The Telomere-Binding Protein Tbf1 Demarcates snoRNA Gene Promoters in Saccharomyces cerevisiae. Mol Cell 38(4):614-620 | + | '''Description of YPL128C:''' Telobox-containing general regulatory factor; binds TTAGGG repeats within subtelomeric anti-silencing regions (STARs), blocking silent chromatin propagation; binds majority of snoRNA gene promoters, required for full snoRNA expression; caps DSB flanked by long T2AG3 repeats and blocks checkpoint activation<ref name='S000074974'>Bilaud T, et al. (1996) The telobox, a Myb-related telomeric DNA binding motif found in proteins from yeast, plants and human. Nucleic Acids Res 24(7):1294-303 {{SGDpaper|S000074974}} PMID 8614633</ref><ref name='S000053340'>Fourel G, et al. (1999) Cohabitation of insulators and silencing elements in yeast subtelomeric regions. EMBO J 18(9):2522-37 {{SGDpaper|S000053340}} PMID 10228166</ref><ref name='S000060749'>Fourel G, et al. (2001) An activation-independent role of transcription factors in insulator function. EMBO Rep 2(2):124-32 {{SGDpaper|S000060749}} PMID 11258704</ref><ref name='S000071586'>Fourel G, et al. (2002) General regulatory factors (GRFs) as genome partitioners. J Biol Chem 277(44):41736-43 {{SGDpaper|S000071586}} PMID 12200417</ref><ref name='S000040662'>Koering CE, et al. (2000) Identification of high affinity Tbf1p-binding sites within the budding yeast genome. Nucleic Acids Res 28(13):2519-26 {{SGDpaper|S000040662}} PMID 10871401</ref><ref name='S000134259'>Preti M, et al. (2010) The Telomere-Binding Protein Tbf1 Demarcates snoRNA Gene Promoters in Saccharomyces cerevisiae. Mol Cell 38(4):614-620 {{SGDpaper|S000134259}} PMID 20513435</ref><ref name='S000146921'>Ribaud V, et al. (2011) DNA-end capping by the budding yeast transcription factor and subtelomeric binding protein Tbf1.LID - 10.1038/emboj.2011.349 [doi] EMBO J () |
| − | {{SGDpaper| | + | {{SGDpaper|S000146921}} PMID 21952045</ref> |
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Revision as of 14:05, 20 October 2011
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| Systematic name | YPL128C |
| Gene name | TBF1 |
| Aliases | LPI16 |
| Feature type | ORF, Verified |
| Coordinates | Chr XVI:308221..306533 |
| Primary SGDID | S000006049 |
Description of YPL128C: Telobox-containing general regulatory factor; binds TTAGGG repeats within subtelomeric anti-silencing regions (STARs), blocking silent chromatin propagation; binds majority of snoRNA gene promoters, required for full snoRNA expression; caps DSB flanked by long T2AG3 repeats and blocks checkpoint activation[1][2][3][4][5][6][7]
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References
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- ↑ Bilaud T, et al. (1996) The telobox, a Myb-related telomeric DNA binding motif found in proteins from yeast, plants and human. Nucleic Acids Res 24(7):1294-303 SGD PMID 8614633
- ↑ Fourel G, et al. (1999) Cohabitation of insulators and silencing elements in yeast subtelomeric regions. EMBO J 18(9):2522-37 SGD PMID 10228166
- ↑ Fourel G, et al. (2001) An activation-independent role of transcription factors in insulator function. EMBO Rep 2(2):124-32 SGD PMID 11258704
- ↑ Fourel G, et al. (2002) General regulatory factors (GRFs) as genome partitioners. J Biol Chem 277(44):41736-43 SGD PMID 12200417
- ↑ Koering CE, et al. (2000) Identification of high affinity Tbf1p-binding sites within the budding yeast genome. Nucleic Acids Res 28(13):2519-26 SGD PMID 10871401
- ↑ Preti M, et al. (2010) The Telomere-Binding Protein Tbf1 Demarcates snoRNA Gene Promoters in Saccharomyces cerevisiae. Mol Cell 38(4):614-620 SGD PMID 20513435
- ↑ Ribaud V, et al. (2011) DNA-end capping by the budding yeast transcription factor and subtelomeric binding protein Tbf1.LID - 10.1038/emboj.2011.349 [doi] EMBO J () SGD PMID 21952045
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