Difference between revisions of "YMR004W"

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'''Description of YMR004W:''' Protein required for sorting proteins to the vacuole; overproduction of Mvp1p suppresses several dominant VPS1 mutations; Mvp1p and Vps1p act in concert to promote membrane traffic to the vacuole<ref name='S000051863'>Ekena K and Stevens TH (1995) The Saccharomyces cerevisiae MVP1 gene interacts with VPS1 and is required for vacuolar protein sorting. Mol Cell Biol 15(3):1671-8
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'''Description of YMR004W:''' Protein required for sorting proteins to the vacuole; overproduction of Mvp1p suppresses several dominant VPS1 mutations; Mvp1p and Vps1p act in concert to promote membrane traffic to the vacuole; participates in transcription initiation and/or early elongation of specific genes; interacts with "foot domain" of RNA polymerase II; deletion results in abnormal CTD-Ser5 phosphorylation of RNA polymerase II at specific promoter regions<ref name='S000051863'>Ekena K and Stevens TH (1995) The Saccharomyces cerevisiae MVP1 gene interacts with VPS1 and is required for vacuolar protein sorting. Mol Cell Biol 15(3):1671-8 {{SGDpaper|S000051863}} PMID 7862158</ref><ref name='S000146910'>Garcia-Lopez MC, et al. (2011) The Conserved Foot Domain of RNA Pol II Associates with Proteins Involved in Transcriptional Initiation and/or Early Elongation. Genetics ()
  {{SGDpaper|S000051863}} PMID 7862158</ref>
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  {{SGDpaper|S000146910}} PMID 21954159</ref>
 
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Revision as of 14:05, 5 October 2011

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Systematic name YMR004W
Gene name MVP1
Aliases
Feature type ORF, Verified
Coordinates Chr XIII:274017..275552
Primary SGDID S000004606


Description of YMR004W: Protein required for sorting proteins to the vacuole; overproduction of Mvp1p suppresses several dominant VPS1 mutations; Mvp1p and Vps1p act in concert to promote membrane traffic to the vacuole; participates in transcription initiation and/or early elongation of specific genes; interacts with "foot domain" of RNA polymerase II; deletion results in abnormal CTD-Ser5 phosphorylation of RNA polymerase II at specific promoter regions[1][2]




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References

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  1. Ekena K and Stevens TH (1995) The Saccharomyces cerevisiae MVP1 gene interacts with VPS1 and is required for vacuolar protein sorting. Mol Cell Biol 15(3):1671-8 SGD PMID 7862158
  2. Garcia-Lopez MC, et al. (2011) The Conserved Foot Domain of RNA Pol II Associates with Proteins Involved in Transcriptional Initiation and/or Early Elongation. Genetics () SGD PMID 21954159

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