Difference between revisions of "YOR204W"

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==Community Commentary==
 
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==References==
 
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Revision as of 08:18, 30 January 2007

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Systematic name YOR204W
Gene name DED1
Aliases SPP81
Feature type ORF, Verified
Coordinates Chr XV:722912..724726


Description of YOR204W: ATP-dependent DEAD (Asp-Glu-Ala-Asp)-box RNA helicase, required for translation initiation of all yeast mRNAs; mutations in human DEAD-box DBY are a frequent cause of male infertility[1][2][3]




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Community Commentary

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References

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  1. Johnstone O, et al. (2005) Belle is a Drosophila DEAD-box protein required for viability and in the germ line. Dev Biol 277(1):92-101 SGD PMID 15572142
  2. Noueiry AO, et al. (2000) A mutant allele of essential, general translation initiation factor DED1 selectively inhibits translation of a viral mRNA. Proc Natl Acad Sci U S A 97(24):12985-90 SGD PMID 11069307
  3. Iost I, et al. (1999) Ded1p, a DEAD-box protein required for translation initiation in Saccharomyces cerevisiae, is an RNA helicase. J Biol Chem 274(25):17677-83 SGD PMID 10364207

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