Difference between revisions of "YOR025W"

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==Community Commentary==
 
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==References==
 
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Revision as of 08:18, 30 January 2007

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Systematic name YOR025W
Gene name HST3
Aliases
Feature type ORF, Verified
Coordinates Chr XV:378219..379562


Description of YOR025W: Member of the Sir2 family of NAD(+)-dependent protein deacetylases; involved along with Hst4p in telomeric silencing, cell cycle progression, radiation resistance, genomic stability and short-chain fatty acid metabolism[1][2][3][4]




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Community Commentary

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References

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  1. Starai VJ, et al. (2003) Short-chain fatty acid activation by acyl-coenzyme A synthetases requires SIR2 protein function in Salmonella enterica and Saccharomyces cerevisiae. Genetics 163(2):545-55 SGD PMID 12618394
  2. Grunweller A and Ehrenhofer-Murray AE (2002) A novel yeast silencer. the 2mu origin of Saccharomyces cerevisiae has HST3-, MIG1- and SIR-dependent silencing activity. Genetics 162(1):59-71 SGD PMID 12242223
  3. Brachmann CB, et al. (1995) The SIR2 gene family, conserved from bacteria to humans, functions in silencing, cell cycle progression, and chromosome stability. Genes Dev 9(23):2888-902 SGD PMID 7498786
  4. Smith JS, et al. (2000) A phylogenetically conserved NAD+-dependent protein deacetylase activity in the Sir2 protein family. Proc Natl Acad Sci U S A 97(12):6658-63 SGD PMID 10841563

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