Difference between revisions of "YOL006C"
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
|nowrap| Chr XV:315388..313079 | |nowrap| Chr XV:315388..313079 | ||
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==Community Commentary== | ==Community Commentary== | ||
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==References== | ==References== | ||
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Revision as of 08:18, 30 January 2007
Share your knowledge...Edit this entry! <protect>
| Systematic name | YOL006C |
| Gene name | TOP1 |
| Aliases | MAK1, MAK17 |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:315388..313079 |
Description of YOL006C: Topoisomerase I, nuclear enzyme that relieves torsional strain in DNA by cleaving and re-sealing the phosphodiester backbone; relaxes both positively and negatively supercoiled DNA; functions in replication, transcription, and recombination[1][2][3]
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Contents
Community Commentary
About Community Commentary. Please share your knowledge!
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References
See Help:References on how to add references
- ↑ Woo MH, et al. (2003) Locking the DNA topoisomerase I protein clamp inhibits DNA rotation and induces cell lethality. Proc Natl Acad Sci U S A 100(24):13767-72 SGD PMID 14585933
- ↑ Roca J (1995) The mechanisms of DNA topoisomerases. Trends Biochem Sci 20(4):156-60 SGD PMID 7770916
- ↑ Thrash C, et al. (1985) Cloning, characterization, and sequence of the yeast DNA topoisomerase I gene. Proc Natl Acad Sci U S A 82(13):4374-8 SGD PMID 2989818
See Help:Categories on how to add the wiki page for this gene to a Category </protect>
