Difference between revisions of "YNL161W"

From SGD-Wiki
Jump to: navigation, search
(Automated import of articles)
(Automated import of articles)
Line 18: Line 18:
 
|}
 
|}
 
<br>
 
<br>
−
'''Description of YNL161W:''' Serine/threonine protein kinase that regulates cell morphogenesis pathways, including cell wall biosynthesis, mating projection morphology, bipolar bud site selection; regulates SRL1 mRNA localization via phosphorylation of substrate Ssd1p<ref name='S000060221'>Bidlingmaier S, et al. (2001) The Cbk1p pathway is important for polarized cell growth and cell separation in Saccharomyces cerevisiae. Mol Cell Biol 21(7):2449-62 {{SGDpaper|S000060221}} PMID 11259593</ref><ref name='S000144483'>Kurischko C, et al. (2011) The yeast Cbk1 kinase regulates mRNA localization via the mRNA-binding protein Ssd1. J Cell Biol 192(4):583-98 {{SGDpaper|S000144483}} PMID 21339329</ref><ref name='S000059135'>Racki WJ, et al. (2000) Cbk1p, a protein similar to the human myotonic dystrophy kinase, is essential for normal morphogenesis in Saccharomyces cerevisiae. EMBO J 19(17):4524-32
+
'''Description of YNL161W:''' Serine/threonine protein kinase of the the RAM signaling network; Ndr/LATS family member; binds regulatory subunit Mob2p; involved in regulation of cellular morphogenesis, polarized growth, and septum destruction; phosphorylation by Cbk1p regulates localization and activity of Ace2p transcription factor and Ssd1p translational repressor; Cbk1p activity is regulated by both phosphorylation and specific localization<ref name='S000060221'>Bidlingmaier S, et al. (2001) The Cbk1p pathway is important for polarized cell growth and cell separation in Saccharomyces cerevisiae. Mol Cell Biol 21(7):2449-62 {{SGDpaper|S000060221}} PMID 11259593</ref><ref name='S000141708'>Brace J, et al. (2011) Mitotic Exit Control of the Saccharomyces cerevisiae Ndr/LATS Kinase Cbk1 Regulates Daughter Cell Separation after Cytokinesis. Mol Cell Biol 31(4):721-735 {{SGDpaper|S000141708}} PMID 21135117</ref><ref name='S000068760'>Colman-Lerner A, et al. (2001) Yeast Cbk1 and Mob2 activate daughter-specific genetic programs to induce asymmetric cell fates. Cell 107(6):739-50 {{SGDpaper|S000068760}} PMID 11747810</ref><ref name='S000119966'>Jansen JM, et al. (2006) Phosphoregulation of Cbk1 is critical for RAM network control of transcription and morphogenesis. J Cell Biol 175(5):755-66 {{SGDpaper|S000119966}} PMID 17145962</ref><ref name='S000132503'>Jansen JM, et al. (2009) Cbk1 regulation of the RNA-binding protein Ssd1 integrates cell fate with translational control. Curr Biol 19(24):2114-20 {{SGDpaper|S000132503}} PMID 19962308</ref><ref name='S000144483'>Kurischko C, et al. (2011) The yeast Cbk1 kinase regulates mRNA localization via the mRNA-binding protein Ssd1. J Cell Biol 192(4):583-98 {{SGDpaper|S000144483}} PMID 21339329</ref><ref name='S000134510'>Mazanka E and Weiss EL (2010) Sequential Counteracting Kinases Restrict an Asymmetric Gene Expression Program to early G1. Mol Biol Cell 21(16):2809-20 {{SGDpaper|S000134510}} PMID 20573982</ref><ref name='S000127452'>Mazanka E, et al. (2008) The NDR/LATS family kinase Cbk1 directly controls transcriptional asymmetry. PLoS Biol 6(8):e203 {{SGDpaper|S000127452}} PMID 18715118</ref><ref name='S000074101'>Nelson B, et al. (2003) RAM: a conserved signaling network that regulates Ace2p transcriptional activity and polarized morphogenesis. Mol Biol Cell 14(9):3782-803 {{SGDpaper|S000074101}} PMID 12972564</ref><ref name='S000132464'>Panozzo C, et al. (2010) Mutations in the C-terminus of the conserved NDR kinase, Cbk1p of Saccharomyces cerevisiae, make the protein independent of upstream activators. Mol Genet Genomics 283(2):111-22 {{SGDpaper|S000132464}} PMID 19967545</ref><ref name='S000059135'>Racki WJ, et al. (2000) Cbk1p, a protein similar to the human myotonic dystrophy kinase, is essential for normal morphogenesis in Saccharomyces cerevisiae. EMBO J 19(17):4524-32 {{SGDpaper|S000059135}} PMID 10970846</ref><ref name='S000070382'>Weiss EL, et al. (2002) The Saccharomyces cerevisiae Mob2p-Cbk1p kinase complex promotes polarized growth and acts with the mitotic exit network to facilitate daughter cell-specific localization of Ace2p transcription factor. J Cell Biol 158(5):885-900
−
  {{SGDpaper|S000059135}} PMID 10970846</ref>
+
  {{SGDpaper|S000070382}} PMID 12196508</ref>
 
<br>
 
<br>
 
<br>
 
<br>

Revision as of 13:05, 2 September 2011

Share your knowledge...Edit this entry! <protect>

Systematic name YNL161W
Gene name CBK1
Aliases
Feature type ORF, Verified
Coordinates Chr XIV:332597..334867
Primary SGDID S000005105


Description of YNL161W: Serine/threonine protein kinase of the the RAM signaling network; Ndr/LATS family member; binds regulatory subunit Mob2p; involved in regulation of cellular morphogenesis, polarized growth, and septum destruction; phosphorylation by Cbk1p regulates localization and activity of Ace2p transcription factor and Ssd1p translational repressor; Cbk1p activity is regulated by both phosphorylation and specific localization[1][2][3][4][5][6][7][8][9][10][11][12]




</protect>

Community Commentary

About Community Commentary. Please share your knowledge!




<protect>

References

See Help:References on how to add references

  1. ↑ Bidlingmaier S, et al. (2001) The Cbk1p pathway is important for polarized cell growth and cell separation in Saccharomyces cerevisiae. Mol Cell Biol 21(7):2449-62 SGD PMID 11259593
  2. ↑ Brace J, et al. (2011) Mitotic Exit Control of the Saccharomyces cerevisiae Ndr/LATS Kinase Cbk1 Regulates Daughter Cell Separation after Cytokinesis. Mol Cell Biol 31(4):721-735 SGD PMID 21135117
  3. ↑ Colman-Lerner A, et al. (2001) Yeast Cbk1 and Mob2 activate daughter-specific genetic programs to induce asymmetric cell fates. Cell 107(6):739-50 SGD PMID 11747810
  4. ↑ Jansen JM, et al. (2006) Phosphoregulation of Cbk1 is critical for RAM network control of transcription and morphogenesis. J Cell Biol 175(5):755-66 SGD PMID 17145962
  5. ↑ Jansen JM, et al. (2009) Cbk1 regulation of the RNA-binding protein Ssd1 integrates cell fate with translational control. Curr Biol 19(24):2114-20 SGD PMID 19962308
  6. ↑ Kurischko C, et al. (2011) The yeast Cbk1 kinase regulates mRNA localization via the mRNA-binding protein Ssd1. J Cell Biol 192(4):583-98 SGD PMID 21339329
  7. ↑ Mazanka E and Weiss EL (2010) Sequential Counteracting Kinases Restrict an Asymmetric Gene Expression Program to early G1. Mol Biol Cell 21(16):2809-20 SGD PMID 20573982
  8. ↑ Mazanka E, et al. (2008) The NDR/LATS family kinase Cbk1 directly controls transcriptional asymmetry. PLoS Biol 6(8):e203 SGD PMID 18715118
  9. ↑ Nelson B, et al. (2003) RAM: a conserved signaling network that regulates Ace2p transcriptional activity and polarized morphogenesis. Mol Biol Cell 14(9):3782-803 SGD PMID 12972564
  10. ↑ Panozzo C, et al. (2010) Mutations in the C-terminus of the conserved NDR kinase, Cbk1p of Saccharomyces cerevisiae, make the protein independent of upstream activators. Mol Genet Genomics 283(2):111-22 SGD PMID 19967545
  11. ↑ Racki WJ, et al. (2000) Cbk1p, a protein similar to the human myotonic dystrophy kinase, is essential for normal morphogenesis in Saccharomyces cerevisiae. EMBO J 19(17):4524-32 SGD PMID 10970846
  12. ↑ Weiss EL, et al. (2002) The Saccharomyces cerevisiae Mob2p-Cbk1p kinase complex promotes polarized growth and acts with the mitotic exit network to facilitate daughter cell-specific localization of Ace2p transcription factor. J Cell Biol 158(5):885-900 SGD PMID 12196508

See Help:Categories on how to add the wiki page for this gene to a Category </protect>

Retrieved from "https://wiki.yeastgenome.org/index.php?title=YNL161W&oldid=320799"