Difference between revisions of "YFL034C-B"

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'''Description of YFL034C-B:''' Component of the RAM signaling network, that activates the Cbk1p kinase, thereby facilitating the Ace2p-dependent daughter cell-specific transcription of genes involved in cell separation; similar to Mob1p<ref name='S000075529'>Schneper L, et al. (2004) The Ras/protein kinase A pathway acts in parallel with the Mob2/Cbk1 pathway to effect cell cycle progression and proper bud site selection. Eukaryot Cell 3(1):108-20 {{SGDpaper|S000075529}} PMID 14871942</ref><ref name='S000070382'>Weiss EL, et al. (2002) The Saccharomyces cerevisiae Mob2p-Cbk1p kinase complex promotes polarized growth and acts with the mitotic exit network to facilitate daughter cell-specific localization of Ace2p transcription factor. J Cell Biol 158(5):885-900
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'''Description of YFL034C-B:''' Activator of Cbk1p kinase; component of the RAM signaling network that regulates cellular polarity and morphogenesis; activation of Cbk1p facilitates the Ace2p-dependent daughter cell-specific transcription of genes involved in cell separation; similar to Mob1p<ref name='S000074101'>Nelson B, et al. (2003) RAM: a conserved signaling network that regulates Ace2p transcriptional activity and polarized morphogenesis. Mol Biol Cell 14(9):3782-803 {{SGDpaper|S000074101}} PMID 12972564</ref><ref name='S000075529'>Schneper L, et al. (2004) The Ras/protein kinase A pathway acts in parallel with the Mob2/Cbk1 pathway to effect cell cycle progression and proper bud site selection. Eukaryot Cell 3(1):108-20 {{SGDpaper|S000075529}} PMID 14871942</ref><ref name='S000070382'>Weiss EL, et al. (2002) The Saccharomyces cerevisiae Mob2p-Cbk1p kinase complex promotes polarized growth and acts with the mitotic exit network to facilitate daughter cell-specific localization of Ace2p transcription factor. J Cell Biol 158(5):885-900
 
  {{SGDpaper|S000070382}} PMID 12196508</ref>
 
  {{SGDpaper|S000070382}} PMID 12196508</ref>
 
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Revision as of 13:05, 26 August 2011

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Systematic name YFL034C-B
Gene name MOB2
Aliases YFL035C, YFL035C-A
Feature type ORF, Verified
Coordinates Chr VI:63993..63016
Primary SGDID S000001859


Description of YFL034C-B: Activator of Cbk1p kinase; component of the RAM signaling network that regulates cellular polarity and morphogenesis; activation of Cbk1p facilitates the Ace2p-dependent daughter cell-specific transcription of genes involved in cell separation; similar to Mob1p[1][2][3]




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References

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  1. Nelson B, et al. (2003) RAM: a conserved signaling network that regulates Ace2p transcriptional activity and polarized morphogenesis. Mol Biol Cell 14(9):3782-803 SGD PMID 12972564
  2. Schneper L, et al. (2004) The Ras/protein kinase A pathway acts in parallel with the Mob2/Cbk1 pathway to effect cell cycle progression and proper bud site selection. Eukaryot Cell 3(1):108-20 SGD PMID 14871942
  3. Weiss EL, et al. (2002) The Saccharomyces cerevisiae Mob2p-Cbk1p kinase complex promotes polarized growth and acts with the mitotic exit network to facilitate daughter cell-specific localization of Ace2p transcription factor. J Cell Biol 158(5):885-900 SGD PMID 12196508

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