Difference between revisions of "YJR140C"
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| − | '''Description of YJR140C:''' Subunit of the HIR complex | + | '''Description of YJR140C:''' Subunit of the HIR complex; a nucleosome assembly complex involved in regulation of histone gene transcription; involved in position-dependent gene silencing and nucleosome reassembly; ortholog of human CABIN1 protein<ref name='S000072261'>Formosa T, et al. (2002) Defects in SPT16 or POB3 (yFACT) in Saccharomyces cerevisiae cause dependence on the Hir/Hpc pathway: polymerase passage may degrade chromatin structure. Genetics 162(4):1557-71 {{SGDpaper|S000072261}} PMID 12524332</ref><ref name='S000043099'>Osley MA and Lycan D (1987) Trans-acting regulatory mutations that alter transcription of Saccharomyces cerevisiae histone genes. Mol Cell Biol 7(12):4204-10 {{SGDpaper|S000043099}} PMID 3125420</ref><ref name='S000087068'>Prochasson P, et al. (2005) The HIR corepressor complex binds to nucleosomes generating a distinct protein/DNA complex resistant to remodeling by SWI/SNF. Genes Dev 19(21):2534-9 {{SGDpaper|S000087068}} PMID 16264190</ref><ref name='S000043367'>Qian Z, et al. (1998) Yeast Ty1 retrotransposition is stimulated by a synergistic interaction between mutations in chromatin assembly factor I and histone regulatory proteins. Mol Cell Biol 18(8):4783-92 {{SGDpaper|S000043367}} PMID 9671488</ref><ref name='S000146273'>Rai TS, et al. (2011) Human CABIN1 is a functional member of the human HIRA/UBN1/ASF1a histone H3.3 chaperone complex. Mol Cell Biol () {{SGDpaper|S000146273}} PMID 21807893</ref><ref name='S000055143'>Spector MS, et al. (1997) Hir1p and Hir2p function as transcriptional corepressors to regulate histone gene transcription in the Saccharomyces cerevisiae cell cycle. Mol Cell Biol 17(2):545-52 {{SGDpaper|S000055143}} PMID 9001207</ref><ref name='S000039430'>Xu H, et al. (1992) Identification of a new set of cell cycle-regulatory genes that regulate S-phase transcription of histone genes in Saccharomyces cerevisiae. Mol Cell Biol 12(11):5249-59 |
{{SGDpaper|S000039430}} PMID 1406694</ref> | {{SGDpaper|S000039430}} PMID 1406694</ref> | ||
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Revision as of 13:05, 16 August 2011
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| Systematic name | YJR140C |
| Gene name | HIR3 |
| Aliases | HPC1 |
| Feature type | ORF, Verified |
| Coordinates | Chr X:695696..690750 |
| Primary SGDID | S000003901 |
Description of YJR140C: Subunit of the HIR complex; a nucleosome assembly complex involved in regulation of histone gene transcription; involved in position-dependent gene silencing and nucleosome reassembly; ortholog of human CABIN1 protein[1][2][3][4][5][6][7]
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References
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- ↑ Formosa T, et al. (2002) Defects in SPT16 or POB3 (yFACT) in Saccharomyces cerevisiae cause dependence on the Hir/Hpc pathway: polymerase passage may degrade chromatin structure. Genetics 162(4):1557-71 SGD PMID 12524332
- ↑ Osley MA and Lycan D (1987) Trans-acting regulatory mutations that alter transcription of Saccharomyces cerevisiae histone genes. Mol Cell Biol 7(12):4204-10 SGD PMID 3125420
- ↑ Prochasson P, et al. (2005) The HIR corepressor complex binds to nucleosomes generating a distinct protein/DNA complex resistant to remodeling by SWI/SNF. Genes Dev 19(21):2534-9 SGD PMID 16264190
- ↑ Qian Z, et al. (1998) Yeast Ty1 retrotransposition is stimulated by a synergistic interaction between mutations in chromatin assembly factor I and histone regulatory proteins. Mol Cell Biol 18(8):4783-92 SGD PMID 9671488
- ↑ Rai TS, et al. (2011) Human CABIN1 is a functional member of the human HIRA/UBN1/ASF1a histone H3.3 chaperone complex. Mol Cell Biol () SGD PMID 21807893
- ↑ Spector MS, et al. (1997) Hir1p and Hir2p function as transcriptional corepressors to regulate histone gene transcription in the Saccharomyces cerevisiae cell cycle. Mol Cell Biol 17(2):545-52 SGD PMID 9001207
- ↑ Xu H, et al. (1992) Identification of a new set of cell cycle-regulatory genes that regulate S-phase transcription of histone genes in Saccharomyces cerevisiae. Mol Cell Biol 12(11):5249-59 SGD PMID 1406694
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