Difference between revisions of "YPL249C"
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− | '''Description of YPL249C:''' GTPase-activating protein (GAP) for yeast Rab family members | + | '''Description of YPL249C:''' GTPase-activating protein (GAP) for yeast Rab family members; involved in ER to Golgi trafficking; exhibits GAP activity toward Ypt1p that is stimulated by Gyl1p, also acts on Sec4p; interacts with Gyl1p, Rvs161p and Rvs167p; involved in recruiting Rvs167p to the bud tip during polarized growth<ref name='S000059091'>Bon E, et al. (2000) A network of proteins around Rvs167p and Rvs161p, two proteins related to the yeast actin cytoskeleton. Yeast 16(13):1229-41 {{SGDpaper|S000059091}} PMID 10992286</ref><ref name='S000071827'>De Antoni A, et al. (2002) Significance of GTP hydrolysis in Ypt1p-regulated endoplasmic reticulum to Golgi transport revealed by the analysis of two novel Ypt1-GAPs. J Biol Chem 277(43):41023-31 {{SGDpaper|S000071827}} PMID 12189143</ref><ref name='S000081252'>Friesen H, et al. (2005) Interaction of the Saccharomyces cerevisiae cortical actin patch protein Rvs167p with proteins involved in ER to Golgi vesicle trafficking. Genetics 170(2):555-68 {{SGDpaper|S000081252}} PMID 15802519</ref><ref name='S000145351'>Prigent M, et al. (2011) The RabGAP proteins Gyp5p and Gyl1p recruit the BAR domain protein Rvs167p for polarized exocytosis.LID - 10.1111/j.1600-0854.2011.01218.x [doi] Traffic () |
− | {{SGDpaper| | + | {{SGDpaper|S000145351}} PMID 21554509</ref> |
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Revision as of 14:05, 15 July 2011
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Systematic name | YPL249C |
Gene name | GYP5 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr XVI:79353..76669 |
Primary SGDID | S000006170 |
Description of YPL249C: GTPase-activating protein (GAP) for yeast Rab family members; involved in ER to Golgi trafficking; exhibits GAP activity toward Ypt1p that is stimulated by Gyl1p, also acts on Sec4p; interacts with Gyl1p, Rvs161p and Rvs167p; involved in recruiting Rvs167p to the bud tip during polarized growth[1][2][3][4]
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References
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- ↑ Bon E, et al. (2000) A network of proteins around Rvs167p and Rvs161p, two proteins related to the yeast actin cytoskeleton. Yeast 16(13):1229-41 SGD PMID 10992286
- ↑ De Antoni A, et al. (2002) Significance of GTP hydrolysis in Ypt1p-regulated endoplasmic reticulum to Golgi transport revealed by the analysis of two novel Ypt1-GAPs. J Biol Chem 277(43):41023-31 SGD PMID 12189143
- ↑ Friesen H, et al. (2005) Interaction of the Saccharomyces cerevisiae cortical actin patch protein Rvs167p with proteins involved in ER to Golgi vesicle trafficking. Genetics 170(2):555-68 SGD PMID 15802519
- ↑ Prigent M, et al. (2011) The RabGAP proteins Gyp5p and Gyl1p recruit the BAR domain protein Rvs167p for polarized exocytosis.LID - 10.1111/j.1600-0854.2011.01218.x [doi] Traffic () SGD PMID 21554509
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