Difference between revisions of "YKR043C"
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| − | '''Description of YKR043C:''' | + | '''Description of YKR043C:''' Sedoheptulose bisphosphatase involved in riboneogenesis; dephosphorylates sedoheptulose 1,7-bisphosphate, which is converted via the nonoxidative pentose phosphate pathway to ribose-5-phosphate; facilitates the conversion of glycolytic intermediates to pentose phosphate units; also has fructose 1,6-bisphosphatase activity but this is probably not biologically relevant, since deletion does not affect FBP levels; GFP-fusion protein localizes to the cytoplasm and nucleus<ref name='S000145725'>Clasquin MF, et al. (2011) Riboneogenesis in yeast. Cell 145(6):969-80 {{SGDpaper|S000145725}} PMID 21663798</ref><ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 {{SGDpaper|S000074185}} PMID 14562095</ref><ref name='S000133929'>Kuznetsova E, et al. (2010) Structure and activity of the metal-independent fructose-1,6-bisphosphatase YK23 from Saccharomyces cerevisiae. J Biol Chem 285(27):21049-59 |
{{SGDpaper|S000133929}} PMID 20427268</ref> | {{SGDpaper|S000133929}} PMID 20427268</ref> | ||
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Revision as of 14:05, 12 July 2011
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| Systematic name | YKR043C |
| Gene name | SHB17 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XI:521712..520897 |
| Primary SGDID | S000001751 |
Description of YKR043C: Sedoheptulose bisphosphatase involved in riboneogenesis; dephosphorylates sedoheptulose 1,7-bisphosphate, which is converted via the nonoxidative pentose phosphate pathway to ribose-5-phosphate; facilitates the conversion of glycolytic intermediates to pentose phosphate units; also has fructose 1,6-bisphosphatase activity but this is probably not biologically relevant, since deletion does not affect FBP levels; GFP-fusion protein localizes to the cytoplasm and nucleus[1][2][3]
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References
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- ↑ Clasquin MF, et al. (2011) Riboneogenesis in yeast. Cell 145(6):969-80 SGD PMID 21663798
- ↑ Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD PMID 14562095
- ↑ Kuznetsova E, et al. (2010) Structure and activity of the metal-independent fructose-1,6-bisphosphatase YK23 from Saccharomyces cerevisiae. J Biol Chem 285(27):21049-59 SGD PMID 20427268
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