Difference between revisions of "YBR204C"
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− | '''Description of YBR204C:''' Serine hydrolase; | + | '''Description of YBR204C:''' Serine hydrolase; exhibits active esterase plus weak triacylglycerol lipase activities; proposed role in lipid homeostasis, regulating phospholipid and non-polar lipid levels and required for mobilization of LD-stored lipids; localizes to the lipid droplet (LD) surface; contains a classical serine containing catalytic triad (GxSxG motif)<ref name='S000076484'>Baxter SM, et al. (2004) Synergistic computational and experimental proteomics approaches for more accurate detection of active serine hydrolases in yeast. Mol Cell Proteomics 3(3):209-25 {{SGDpaper|S000076484}} PMID 14645503</ref><ref name='S000145076'>Debelyy MO, et al. (2011) Involvement of the yeast hydrolase Ldh1p in lipid homeostasis. Eukaryot Cell () {{SGDpaper|S000145076}} PMID 21478434</ref><ref name='S000071347'>Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91 |
{{SGDpaper|S000071347}} PMID 12140549</ref> | {{SGDpaper|S000071347}} PMID 12140549</ref> | ||
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Revision as of 14:05, 9 May 2011
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Systematic name | YBR204C |
Gene name | LDH1 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr II:633381..632254 |
Primary SGDID | S000000408 |
Description of YBR204C: Serine hydrolase; exhibits active esterase plus weak triacylglycerol lipase activities; proposed role in lipid homeostasis, regulating phospholipid and non-polar lipid levels and required for mobilization of LD-stored lipids; localizes to the lipid droplet (LD) surface; contains a classical serine containing catalytic triad (GxSxG motif)[1][2][3]
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References
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- ↑ Baxter SM, et al. (2004) Synergistic computational and experimental proteomics approaches for more accurate detection of active serine hydrolases in yeast. Mol Cell Proteomics 3(3):209-25 SGD PMID 14645503
- ↑ Debelyy MO, et al. (2011) Involvement of the yeast hydrolase Ldh1p in lipid homeostasis. Eukaryot Cell () SGD PMID 21478434
- ↑ Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91 SGD PMID 12140549
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