Difference between revisions of "YOL027C"
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| − | '''Description of YOL027C:''' Mitochondrial | + | '''Description of YOL027C:''' Mitochondrial protein, forms a complex with Mba1p to facilitate recruitment of mRNA-specific translational activators to ribosomes; roles in protein export and K+/H+ exchange; human ortholog Letm1 implicated in Wolf-Hirschhorn syndrome<ref name='S000136876'>Bauerschmitt H, et al. (2010) Ribosome-binding proteins Mdm38 and Mba1 display overlapping functions for regulation of mitochondrial translation. Mol Biol Cell 21(12):1937-44 {{SGDpaper|S000136876}} PMID 20427570</ref><ref name='S000071517'>Dimmer KS, et al. (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53 {{SGDpaper|S000071517}} PMID 11907266</ref><ref name='S000114395'>Frazier AE, et al. (2006) Mdm38 interacts with ribosomes and is a component of the mitochondrial protein export machinery. J Cell Biol 172(4):553-64 {{SGDpaper|S000114395}} PMID 16476776</ref><ref name='S000082022'>Froschauer E, et al. (2005) Electroneutral K+/H+ exchange in mitochondrial membrane vesicles involves Yol027/Letm1 proteins. Biochim Biophys Acta 1711(1):41-8 {{SGDpaper|S000082022}} PMID 15904662</ref><ref name='S000076911'>Nowikovsky K, et al. (2004) The LETM1/YOL027 gene family encodes a factor of the mitochondrial K+ homeostasis with a potential role in the Wolf-Hirschhorn syndrome. J Biol Chem 279(29):30307-15 |
{{SGDpaper|S000076911}} PMID 15138253</ref> | {{SGDpaper|S000076911}} PMID 15138253</ref> | ||
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Revision as of 14:05, 1 April 2011
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| Systematic name | YOL027C |
| Gene name | MDM38 |
| Aliases | MKH1 |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:273724..272003 |
| Primary SGDID | S000005387 |
Description of YOL027C: Mitochondrial protein, forms a complex with Mba1p to facilitate recruitment of mRNA-specific translational activators to ribosomes; roles in protein export and K+/H+ exchange; human ortholog Letm1 implicated in Wolf-Hirschhorn syndrome[1][2][3][4][5]
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References
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- ↑ Bauerschmitt H, et al. (2010) Ribosome-binding proteins Mdm38 and Mba1 display overlapping functions for regulation of mitochondrial translation. Mol Biol Cell 21(12):1937-44 SGD PMID 20427570
- ↑ Dimmer KS, et al. (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53 SGD PMID 11907266
- ↑ Frazier AE, et al. (2006) Mdm38 interacts with ribosomes and is a component of the mitochondrial protein export machinery. J Cell Biol 172(4):553-64 SGD PMID 16476776
- ↑ Froschauer E, et al. (2005) Electroneutral K+/H+ exchange in mitochondrial membrane vesicles involves Yol027/Letm1 proteins. Biochim Biophys Acta 1711(1):41-8 SGD PMID 15904662
- ↑ Nowikovsky K, et al. (2004) The LETM1/YOL027 gene family encodes a factor of the mitochondrial K+ homeostasis with a potential role in the Wolf-Hirschhorn syndrome. J Biol Chem 279(29):30307-15 SGD PMID 15138253
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