Difference between revisions of "YPR019W"
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| − | '''Description of YPR019W:''' Essential helicase component of heterohexameric MCM2-7 complexes which bind pre-replication complexes on DNA and melt | + | '''Description of YPR019W:''' Essential helicase component of heterohexameric MCM2-7 complexes which bind pre-replication complexes on DNA and melt DNA prior to replication; forms an Mcm4p-6p-7p subcomplex; shows nuclear accumulation in G1; homolog of S. pombe Cdc21p<ref name='S000136716'>Ma X, et al. (2010) The effects of oligomerization on Saccharomyces cerevisiae Mcm4/6/7 function. BMC Biochem 11():37 {{SGDpaper|S000136716}} PMID 20860810</ref><ref name='S000069529'>Tanaka S and Diffley JF (2002) Interdependent nuclear accumulation of budding yeast Cdt1 and Mcm2-7 during G1 phase. Nat Cell Biol 4(3):198-207 {{SGDpaper|S000069529}} PMID 11836525</ref><ref name='S000042473'>Tye BK (1999) MCM proteins in DNA replication. Annu Rev Biochem 68:649-86 |
{{SGDpaper|S000042473}} PMID 10872463</ref> | {{SGDpaper|S000042473}} PMID 10872463</ref> | ||
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Revision as of 13:05, 16 March 2011
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| Systematic name | YPR019W |
| Gene name | MCM4 |
| Aliases | CDC54, HCD21 |
| Feature type | ORF, Verified |
| Coordinates | Chr XVI:596750..599551 |
| Primary SGDID | S000006223 |
Description of YPR019W: Essential helicase component of heterohexameric MCM2-7 complexes which bind pre-replication complexes on DNA and melt DNA prior to replication; forms an Mcm4p-6p-7p subcomplex; shows nuclear accumulation in G1; homolog of S. pombe Cdc21p[1][2][3]
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References
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- ↑ Ma X, et al. (2010) The effects of oligomerization on Saccharomyces cerevisiae Mcm4/6/7 function. BMC Biochem 11():37 SGD PMID 20860810
- ↑ Tanaka S and Diffley JF (2002) Interdependent nuclear accumulation of budding yeast Cdt1 and Mcm2-7 during G1 phase. Nat Cell Biol 4(3):198-207 SGD PMID 11836525
- ↑ Tye BK (1999) MCM proteins in DNA replication. Annu Rev Biochem 68:649-86 SGD PMID 10872463
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