Difference between revisions of "YJL084C"
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| − | '''Description of YJL084C:''' | + | '''Description of YJL084C:''' Alpha arrestin that controls nutrient-mediated intracellular sorting of permease Gap1p; interacts with AP-1 subunit Apl4p; phosphorylated by Npr1p and also by cyclin-CDK complex Pcl7p-Pho85p; promotes endocytosis of plasma membrane proteins<ref name='S000138851'>Hatakeyama R, et al. (2010) Endocytosis of the Aspartic Acid/Glutamic Acid Transporter Dip5 Is Triggered by Substrate-Dependent Recruitment of the Rsp5 Ubiquitin Ligase via the Arrestin-Like Protein Aly2. Mol Cell Biol 30(24):5598-607 {{SGDpaper|S000138851}} PMID 20956561</ref><ref name='S000136012'>O'Donnell AF, et al. (2010) {alpha}-Arrestins Aly1 and Aly2 Regulate Intracellular Trafficking in Response to Nutrient Signaling. Mol Biol Cell 21(20):3552-66 {{SGDpaper|S000136012}} PMID 20739461</ref><ref name='S000070355'>Shi XZ and Ao SZ (2002) Analysis of phosphorylation of YJL084c, a yeast protein. Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai) 34(4):433-8 |
{{SGDpaper|S000070355}} PMID 12098764</ref> | {{SGDpaper|S000070355}} PMID 12098764</ref> | ||
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Revision as of 13:05, 14 March 2011
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| Systematic name | YJL084C |
| Gene name | ALY2 |
| Aliases | ART3 |
| Feature type | ORF, Verified |
| Coordinates | Chr X:278002..274862 |
| Primary SGDID | S000003620 |
Description of YJL084C: Alpha arrestin that controls nutrient-mediated intracellular sorting of permease Gap1p; interacts with AP-1 subunit Apl4p; phosphorylated by Npr1p and also by cyclin-CDK complex Pcl7p-Pho85p; promotes endocytosis of plasma membrane proteins[1][2][3]
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Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [4] [5]
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References
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- ↑ Hatakeyama R, et al. (2010) Endocytosis of the Aspartic Acid/Glutamic Acid Transporter Dip5 Is Triggered by Substrate-Dependent Recruitment of the Rsp5 Ubiquitin Ligase via the Arrestin-Like Protein Aly2. Mol Cell Biol 30(24):5598-607 SGD PMID 20956561
- ↑ O'Donnell AF, et al. (2010) {alpha}-Arrestins Aly1 and Aly2 Regulate Intracellular Trafficking in Response to Nutrient Signaling. Mol Biol Cell 21(20):3552-66 SGD PMID 20739461
- ↑ Shi XZ and Ao SZ (2002) Analysis of phosphorylation of YJL084c, a yeast protein. Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai) 34(4):433-8 SGD PMID 12098764
- ↑ Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
- ↑ submitted by Jeff Ubersax on 2004-01-27
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