Difference between revisions of "YGR216C"

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==Community Commentary==
 
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==References==
 
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Revision as of 08:17, 30 January 2007

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Systematic name YGR216C
Gene name GPI1
Aliases
Feature type ORF, Verified
Coordinates Chr VII:924467..922638


Description of YGR216C: Membrane protein involved in the synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the synthesis of glycosylphosphatidylinositol (GPI) anchors; human and mouse GPI1p are functional homologs[1][2][3][4]




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Community Commentary

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References

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  1. Watanabe R, et al. (1998) The first step of glycosylphosphatidylinositol biosynthesis is mediated by a complex of PIG-A, PIG-H, PIG-C and GPI1. EMBO J 17(4):877-85 SGD PMID 9463366
  2. Leidich SD, et al. (1994) A conditionally lethal yeast mutant blocked at the first step in glycosyl phosphatidylinositol anchor synthesis. J Biol Chem 269(14):10193-6 SGD PMID 8144596
  3. Leidich SD and Orlean P (1996) Gpi1, a Saccharomyces cerevisiae protein that participates in the first step in glycosylphosphatidylinositol anchor synthesis. J Biol Chem 271(44):27829-37 SGD PMID 8910381
  4. Tiede A, et al. (1998) Human and mouse Gpi1p homologues restore glycosylphosphatidylinositol membrane anchor biosynthesis in yeast mutants. Biochem J 334 ( Pt 3)():609-16 SGD PMID 9729469

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