Difference between revisions of "YPR041W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr XVI:648701..649918
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|nowrap| Chr XVI:648704..649921
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000006245
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000006245

Revision as of 14:05, 3 February 2011

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Systematic name YPR041W
Gene name TIF5
Aliases SUI5
Feature type ORF, Verified
Coordinates Chr XVI:648704..649921
Primary SGDID S000006245


Description of YPR041W: Translation initiation factor eIF5; functions both as a GTPase-activating protein to mediate hydrolysis of ribosome-bound GTP and as a GDP dissociation inhibitor to prevent recycling of eIF2[1][2][3]




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References

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  1. Asano K, et al. (2000) A multifactor complex of eukaryotic initiation factors, eIF1, eIF2, eIF3, eIF5, and initiator tRNA(Met) is an important translation initiation intermediate in vivo. Genes Dev 14(19):2534-46 SGD PMID 11018020
  2. Das S, et al. (2001) Eukaryotic translation initiation factor 5 functions as a GTPase-activating protein. J Biol Chem 276(9):6720-6 SGD PMID 11092890
  3. Jennings MD and Pavitt GD (2010) eIF5 has GDI activity necessary for translational control by eIF2 phosphorylation. Nature 465(7296):378-81 SGD PMID 20485439

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