Difference between revisions of "YPL157W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr XVI:254813..255760
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|nowrap| Chr XVI:254814..255761
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000006078
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000006078

Revision as of 14:05, 3 February 2011

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Systematic name YPL157W
Gene name TGS1
Aliases
Feature type ORF, Verified
Coordinates Chr XVI:254814..255761
Primary SGDID S000006078


Description of YPL157W: Trimethyl guanosine synthase, conserved nucleolar methyl transferase that converts the m(7)G cap structure of snRNAs, snoRNAs, and telomerase TLC1 RNA to m(2,2,7)G; also required for ribosome synthesis and nucleolar morphology[1][2][3]




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References

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  1. Colau G, et al. (2004) The small nucle(ol)ar RNA cap trimethyltransferase is required for ribosome synthesis and intact nucleolar morphology. Mol Cell Biol 24(18):7976-86 SGD PMID 15340060
  2. Franke J, et al. (2008) Hypermethylation of yeast telomerase RNA by the snRNA and snoRNA methyltransferase Tgs1. J Cell Sci 121(Pt 21):3553-60 SGD PMID 18840651
  3. Mouaikel J, et al. (2002) Hypermethylation of the cap structure of both yeast snRNAs and snoRNAs requires a conserved methyltransferase that is localized to the nucleolus. Mol Cell 9(4):891-901 SGD PMID 11983179

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