Difference between revisions of "YNR057C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr XIV:734070..733357
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|nowrap| Chr XIV:734069..733356
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000005340
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000005340

Revision as of 14:05, 3 February 2011

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Systematic name YNR057C
Gene name BIO4
Aliases
Feature type ORF, Verified
Coordinates Chr XIV:734069..733356
Primary SGDID S000005340


Description of YNR057C: Dethiobiotin synthetase, catalyzes the third step in the biotin biosynthesis pathway; BIO4 is in a cluster of 3 genes (BIO3, BIO4, and BIO5) that mediate biotin synthesis; expression appears to be repressed at low iron levels[1][2]




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Community Commentary

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Other

Gene Origin

Horizontally transferred from alpha proteobacteria [3] [4]





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References

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  1. Phalip V, et al. (1999) Characterization of the biotin biosynthesis pathway in Saccharomyces cerevisiae and evidence for a cluster containing BIO5, a novel gene involved in vitamer uptake. Gene 232(1):43-51 SGD PMID 10333520
  2. Shakoury-Elizeh M, et al. (2004) Transcriptional remodeling in response to iron deprivation in Saccharomyces cerevisiae. Mol Biol Cell 15(3):1233-43 SGD PMID 14668481
  3. Hall C, et al. (2005) Contribution of horizontal gene transfer to the evolution of Saccharomyces cerevisiae. Eukaryot Cell 4(6):1102-15 SGD PMID 15947202
  4. submitted by Charles Hall on 2006-06-09

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