Difference between revisions of "YNR026C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr XIV:674692..673277
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|nowrap| Chr XIV:674689..673274
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000005309
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000005309

Revision as of 13:05, 3 February 2011

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Systematic name YNR026C
Gene name SEC12
Aliases SED2
Feature type ORF, Verified
Coordinates Chr XIV:674689..673274
Primary SGDID S000005309


Description of YNR026C: Guanine nucleotide exchange factor (GEF), activates Sar1p by catalyzing the exchange of GDP for GTP; required for the initiation of COPII vesicle formation in ER to Golgi transport; glycosylated integral membrane protein of the ER[1][2]




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References

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  1. Barlowe C and Schekman R (1993) SEC12 encodes a guanine-nucleotide-exchange factor essential for transport vesicle budding from the ER. Nature 365(6444):347-9 SGD PMID 8377826
  2. d'Enfert C, et al. (1991) Sec12p-dependent membrane binding of the small GTP-binding protein Sar1p promotes formation of transport vesicles from the ER. J Cell Biol 114(4):663-70 SGD PMID 1907973

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