Difference between revisions of "YKL084W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr XI:280153..280503
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|nowrap| Chr XI:280509..280859
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000001567
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000001567

Revision as of 14:05, 3 February 2011

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Systematic name YKL084W
Gene name HOT13
Aliases
Feature type ORF, Verified
Coordinates Chr XI:280509..280859
Primary SGDID S000001567


Description of YKL084W: Zinc-binding mitochondrial intermembrane space (IMS) protein involved in a disulfide relay system for IMS import of cysteine-containing proteins; binds Mia40p and stimulates its Erv1p-dependent oxidation, probably by sequestering zinc[1][2]




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References

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  1. Curran SP, et al. (2004) The role of Hot13p and redox chemistry in the mitochondrial TIM22 import pathway. J Biol Chem 279(42):43744-51 SGD PMID 15294910
  2. Mesecke N, et al. (2008) The zinc-binding protein Hot13 promotes oxidation of the mitochondrial import receptor Mia40. EMBO Rep 9(11):1107-13 SGD PMID 18787558

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