Difference between revisions of "YIR033W"
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr IX: | + | |nowrap| Chr IX:416124..419465 |
|- | |- | ||
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000001472 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000001472 | ||
Revision as of 13:05, 3 February 2011
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| Systematic name | YIR033W |
| Gene name | MGA2 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr IX:416124..419465 |
| Primary SGDID | S000001472 |
Description of YIR033W: ER membrane protein involved in regulation of OLE1 transcription, acts with homolog Spt23p; inactive ER form dimerizes and one subunit is then activated by ubiquitin/proteasome-dependent processing followed by nuclear targeting[1][2]
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Contents
Community Commentary
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References
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- ↑ Chellappa R, et al. (2001) The membrane proteins, Spt23p and Mga2p, play distinct roles in the activation of Saccharomyces cerevisiae OLE1 gene expression. Fatty acid-mediated regulation of Mga2p activity is independent of its proteolytic processing into a soluble transcription activator. J Biol Chem 276(47):43548-56 SGD PMID 11557770
- ↑ Shcherbik N, et al. (2003) Rsp5p is required for ER bound Mga2p120 polyubiquitination and release of the processed/tethered transactivator Mga2p90. Curr Biol 13(14):1227-33 SGD PMID 12867034
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