Difference between revisions of "YJL087C"
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| − | '''Description of YJL087C:''' tRNA ligase, required for tRNA splicing | + | '''Description of YJL087C:''' tRNA ligase, required for tRNA splicing and for both splicing and translation of HAC1 mRNA in the UPR; has phosphodiesterase, polynucleotide kinase, and ligase activities; localized at the inner nuclear envelope and partially to polysomes<ref name='S000057073'>Clark MW and Abelson J (1987) The subnuclear localization of tRNA ligase in yeast. J Cell Biol 105(4):1515-26 {{SGDpaper|S000057073}} PMID 3312232</ref><ref name='S000136483'>Mori T, et al. (2010) Dual Functions of Yeast tRNA Ligase in the Unfolded Protein Response: Unconventional Cytoplasmic Splicing of HAC1 Pre-mRNA Is Not Sufficient to Release Translational Attenuation. Mol Biol Cell 21(21):3722-34 {{SGDpaper|S000136483}} PMID 20844078</ref><ref name='S000056811'>Xu Q, et al. (1990) Domain structure in yeast tRNA ligase. Biochemistry 29(26):6132-8 |
{{SGDpaper|S000056811}} PMID 2207062</ref> | {{SGDpaper|S000056811}} PMID 2207062</ref> | ||
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Revision as of 13:05, 2 February 2011
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| Systematic name | YJL087C |
| Gene name | TRL1 |
| Aliases | LIG1, RLG1 |
| Feature type | ORF, Verified |
| Coordinates | Chr X:272479..269996 |
| Primary SGDID | S000003623 |
Description of YJL087C: tRNA ligase, required for tRNA splicing and for both splicing and translation of HAC1 mRNA in the UPR; has phosphodiesterase, polynucleotide kinase, and ligase activities; localized at the inner nuclear envelope and partially to polysomes[1][2][3]
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References
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- ↑ Clark MW and Abelson J (1987) The subnuclear localization of tRNA ligase in yeast. J Cell Biol 105(4):1515-26 SGD PMID 3312232
- ↑ Mori T, et al. (2010) Dual Functions of Yeast tRNA Ligase in the Unfolded Protein Response: Unconventional Cytoplasmic Splicing of HAC1 Pre-mRNA Is Not Sufficient to Release Translational Attenuation. Mol Biol Cell 21(21):3722-34 SGD PMID 20844078
- ↑ Xu Q, et al. (1990) Domain structure in yeast tRNA ligase. Biochemistry 29(26):6132-8 SGD PMID 2207062
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