Difference between revisions of "YAR002W"
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| − | '''Description of YAR002W:''' Subunit of the nuclear pore complex (NPC), functions to anchor Nup2p to the NPC in a process controlled by the nucleoplasmic concentration of Gsp1p-GTP; involved in nuclear export and cytoplasmic localization of specific mRNAs such as ASH1<ref name='S000061235'>Denning D, et al. (2001) The nucleoporin Nup60p functions as a Gsp1p-GTP-sensitive tether for Nup2p at the nuclear pore complex. J Cell Biol 154(5):937-50 {{SGDpaper|S000061235}} PMID 11535617</ref><ref name='S000139600'>Powrie EA, et al. ( | + | '''Description of YAR002W:''' Subunit of the nuclear pore complex (NPC), functions to anchor Nup2p to the NPC in a process controlled by the nucleoplasmic concentration of Gsp1p-GTP; involved in nuclear export and cytoplasmic localization of specific mRNAs such as ASH1<ref name='S000061235'>Denning D, et al. (2001) The nucleoporin Nup60p functions as a Gsp1p-GTP-sensitive tether for Nup2p at the nuclear pore complex. J Cell Biol 154(5):937-50 {{SGDpaper|S000061235}} PMID 11535617</ref><ref name='S000139600'>Powrie EA, et al. (2011) A nucleoporin, Nup60p, affects the nuclear and cytoplasmic localization of ASH1 mRNA in S. cerevisiae. RNA 17(1):134-44 |
{{SGDpaper|S000139600}} PMID 21036941</ref> | {{SGDpaper|S000139600}} PMID 21036941</ref> | ||
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Revision as of 13:05, 18 December 2010
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| Systematic name | YAR002W |
| Gene name | NUP60 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr I:152259..153878 |
| Primary SGDID | S000000063 |
Description of YAR002W: Subunit of the nuclear pore complex (NPC), functions to anchor Nup2p to the NPC in a process controlled by the nucleoplasmic concentration of Gsp1p-GTP; involved in nuclear export and cytoplasmic localization of specific mRNAs such as ASH1[1][2]
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Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [3] [4]
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References
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- ↑ Denning D, et al. (2001) The nucleoporin Nup60p functions as a Gsp1p-GTP-sensitive tether for Nup2p at the nuclear pore complex. J Cell Biol 154(5):937-50 SGD PMID 11535617
- ↑ Powrie EA, et al. (2011) A nucleoporin, Nup60p, affects the nuclear and cytoplasmic localization of ASH1 mRNA in S. cerevisiae. RNA 17(1):134-44 SGD PMID 21036941
- ↑ Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
- ↑ submitted by Jeff Ubersax on 2004-01-21
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