Difference between revisions of "YAL015C"
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''NTG1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''NTG1 '' | ||
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases''' ||''FUN33, SCR1'' | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases''' ||''FUN33, SCR1, ogg2'' |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type''' || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]] | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type''' || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]] | ||
Revision as of 13:05, 19 November 2010
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| Systematic name | YAL015C |
| Gene name | NTG1 |
| Aliases | FUN33, SCR1, ogg2 |
| Feature type | ORF, Verified |
| Coordinates | Chr I:128103..126904 |
| Primary SGDID | S000000013 |
Description of YAL015C: DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase involved in base excision repair; acts in both nucleus and mitochondrion; creates a double-strand break at mtDNA origins that stimulates replication in response to oxidative stress[1][2][3][4]
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Contents
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References
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- ↑ Alseth I, et al. (1999) The Saccharomyces cerevisiae homologues of endonuclease III from Escherichia coli, Ntg1 and Ntg2, are both required for efficient repair of spontaneous and induced oxidative DNA damage in yeast. Mol Cell Biol 19(5):3779-87 SGD PMID 10207101
- ↑ Griffiths LM, et al. (2009) Dynamic compartmentalization of base excision repair proteins in response to nuclear and mitochondrial oxidative stress. Mol Cell Biol 29(3):794-807 SGD PMID 19029246
- ↑ Hori A, et al. (2009) Reactive oxygen species regulate DNA copy number in isolated yeast mitochondria by triggering recombination-mediated replication. Nucleic Acids Res 37(3):749-61 SGD PMID 19074198
- ↑ Meadows KL, et al. (2003) Characterization of AP lyase activities of Saccharomyces cerevisiae Ntg1p and Ntg2p: implications for biological function. Nucleic Acids Res 31(19):5560-7 SGD PMID 14500818
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