Difference between revisions of "YFL023W"

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'''Description of YFL023W:''' Protein involved in bud-site selection, nutrient signaling, and gene expression controlled by TOR kinase; diploid mutants show a random budding pattern rather than the wild-type bipolar pattern; plays a role in regulating Ty1 transposition<ref name='S000061390'>Ni L and Snyder M (2001) A genomic study of the bipolar bud site selection pattern in Saccharomyces cerevisiae. Mol Biol Cell 12(7):2147-70 {{SGDpaper|S000061390}} PMID 11452010</ref><ref name='S000125260'>Nyswaner KM, et al. (2008) Chromatin-associated genes protect the yeast genome from ty1 insertional mutagenesis. Genetics 178(1):197-214
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'''Description of YFL023W:''' Unconventional prefoldin protein involved in translation initiation; mutants have inappropriate expression of nutrient sensitive genes due to translational derepression of Gcn4p transcription factor; diploid mutants show random budding<ref name='S000130035'>Deplazes A, et al. (2009) Yeast Uri1p promotes translation initiation and may provide a link to cotranslational quality control. EMBO J 28(10):1429-41 {{SGDpaper|S000130035}} PMID 19387492</ref><ref name='S000075137'>Gstaiger M, et al. (2003) Control of nutrient-sensitive transcription programs by the unconventional prefoldin URI. Science 302(5648):1208-12 {{SGDpaper|S000075137}} PMID 14615539</ref><ref name='S000061390'>Ni L and Snyder M (2001) A genomic study of the bipolar bud site selection pattern in Saccharomyces cerevisiae. Mol Biol Cell 12(7):2147-70
  {{SGDpaper|S000125260}} PMID 18202368</ref>
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  {{SGDpaper|S000061390}} PMID 11452010</ref>
 
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Revision as of 13:05, 8 July 2010

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Systematic name YFL023W
Gene name BUD27
Aliases URI1
Feature type ORF, Verified
Coordinates Chr VI:90984..93374
Primary SGDID S000001871


Description of YFL023W: Unconventional prefoldin protein involved in translation initiation; mutants have inappropriate expression of nutrient sensitive genes due to translational derepression of Gcn4p transcription factor; diploid mutants show random budding[1][2][3]




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References

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  1. Deplazes A, et al. (2009) Yeast Uri1p promotes translation initiation and may provide a link to cotranslational quality control. EMBO J 28(10):1429-41 SGD PMID 19387492
  2. Gstaiger M, et al. (2003) Control of nutrient-sensitive transcription programs by the unconventional prefoldin URI. Science 302(5648):1208-12 SGD PMID 14615539
  3. Ni L and Snyder M (2001) A genomic study of the bipolar bud site selection pattern in Saccharomyces cerevisiae. Mol Biol Cell 12(7):2147-70 SGD PMID 11452010

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