Difference between revisions of "YPR180W"
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| − | '''Description of YPR180W:''' | + | '''Description of YPR180W:''' Subunit of a heterodimeric nuclear SUMO activating enzyme (E1) with Uba2p; activates Smt3p (SUMO) before its conjugation to proteins (sumoylation), which may play a role in protein targeting; essential for viability<ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 {{SGDpaper|S000074185}} PMID 14562095</ref><ref name='S000040819'>Johnson ES, et al. (1997) The ubiquitin-like protein Smt3p is activated for conjugation to other proteins by an Aos1p/Uba2p heterodimer. EMBO J 16(18):5509-19 |
{{SGDpaper|S000040819}} PMID 9312010</ref> | {{SGDpaper|S000040819}} PMID 9312010</ref> | ||
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Revision as of 13:05, 7 July 2010
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| Systematic name | YPR180W |
| Gene name | AOS1 |
| Aliases | RHC31 |
| Feature type | ORF, Verified |
| Coordinates | Chr XVI:895957..897000 |
| Primary SGDID | S000006384 |
Description of YPR180W: Subunit of a heterodimeric nuclear SUMO activating enzyme (E1) with Uba2p; activates Smt3p (SUMO) before its conjugation to proteins (sumoylation), which may play a role in protein targeting; essential for viability[1][2]
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References
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- ↑ Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD PMID 14562095
- ↑ Johnson ES, et al. (1997) The ubiquitin-like protein Smt3p is activated for conjugation to other proteins by an Aos1p/Uba2p heterodimer. EMBO J 16(18):5509-19 SGD PMID 9312010
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