Difference between revisions of "YOR075W"
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| − | '''Description of YOR075W:''' t-SNARE required for ER membrane fusion | + | '''Description of YOR075W:''' t-SNARE required for retrograde vesicular traffic and homotypic ER membrane fusion; forms a complex with the SNAREs Sec22p, Sec20p and Use1p to mediate fusion of Golgi-derived vesicles at the ER<ref name='S000073644'>Dilcher M, et al. (2003) Use1p is a yeast SNARE protein required for retrograde traffic to the ER. EMBO J 22(14):3664-74 {{SGDpaper|S000073644}} PMID 12853481</ref><ref name='S000047931'>Downing TA and Storms RK (1996) Molecular analysis of UFE1, a Saccharomyces cerevisiae gene essential for spore formation and vegetative growth. Curr Genet 30(5):396-403 {{SGDpaper|S000047931}} PMID 8929391</ref><ref name='S000057833'>Lewis MJ and Pelham HR (1996) SNARE-mediated retrograde traffic from the Golgi complex to the endoplasmic reticulum. Cell 85(2):205-15 {{SGDpaper|S000057833}} PMID 8612273</ref><ref name='S000062169'>Patel SK, et al. (1998) Organelle membrane fusion: a novel function for the syntaxin homolog Ufe1p in ER membrane fusion. Cell 92(5):611-20 |
{{SGDpaper|S000062169}} PMID 9506516</ref> | {{SGDpaper|S000062169}} PMID 9506516</ref> | ||
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Revision as of 13:05, 1 July 2010
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| Systematic name | YOR075W |
| Gene name | UFE1 |
| Aliases | YOR29-26 |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:468214..469254 |
| Primary SGDID | S000005601 |
Description of YOR075W: t-SNARE required for retrograde vesicular traffic and homotypic ER membrane fusion; forms a complex with the SNAREs Sec22p, Sec20p and Use1p to mediate fusion of Golgi-derived vesicles at the ER[1][2][3][4]
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Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [5] [6]
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References
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- ↑ Dilcher M, et al. (2003) Use1p is a yeast SNARE protein required for retrograde traffic to the ER. EMBO J 22(14):3664-74 SGD PMID 12853481
- ↑ Downing TA and Storms RK (1996) Molecular analysis of UFE1, a Saccharomyces cerevisiae gene essential for spore formation and vegetative growth. Curr Genet 30(5):396-403 SGD PMID 8929391
- ↑ Lewis MJ and Pelham HR (1996) SNARE-mediated retrograde traffic from the Golgi complex to the endoplasmic reticulum. Cell 85(2):205-15 SGD PMID 8612273
- ↑ Patel SK, et al. (1998) Organelle membrane fusion: a novel function for the syntaxin homolog Ufe1p in ER membrane fusion. Cell 92(5):611-20 SGD PMID 9506516
- ↑ Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
- ↑ submitted by Jeff Ubersax on 2004-01-29
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