Difference between revisions of "YLR425W"
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==Community Commentary== | ==Community Commentary== |
Revision as of 10:51, 24 January 2007
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Systematic name | YLR425W | |
Gene name | TUS1 | |
Aliases | SOP10 | |
Feature type | ORF, Verified | |
Coordinates | Chr XII:982891..986814 | |
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Description of YLR425W: Guanine nucleotide exchange factor (GEF) that functions to modulate Rho1p activity as part of the cell integrity signaling pathway; multicopy suppressor of tor2 mutation and ypk1 ypk2 double mutation; potential Cdc28p substrate[1][2][3]
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Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [1] [4]
References
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- ↑ 1.0 1.1 Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
- ↑ Schmelzle T, et al. (2002) Yeast protein kinases and the RHO1 exchange factor TUS1 are novel components of the cell integrity pathway in yeast. Mol Cell Biol 22(5):1329-39 SGD PMID 11839800
- ↑ Helliwell SB, et al. (1998) TOR2 is part of two related signaling pathways coordinating cell growth in Saccharomyces cerevisiae. Genetics 148(1):99-112 SGD PMID 9475724
- ↑ submitted by Jeff Ubersax on 2004-01-29
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