Difference between revisions of "YOR089C"
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− | '''Description of YOR089C:''' GTPase required for transport | + | '''Description of YOR089C:''' Rab family GTPase required for endocytic transport and for sorting of vacuolar hydrolases; localized in endocytic intermediates; detected in mitochondria; geranylgeranylation required for membrane association; mammalian Rab5 homolog<ref name='S000041251'>Horazdovsky BF, et al. (1994) VPS21 encodes a rab5-like GTP binding protein that is required for the sorting of yeast vacuolar proteins. EMBO J 13(6):1297-309 {{SGDpaper|S000041251}} PMID 8137814</ref><ref name='S000070388'>Neukamm B, et al. (2002) Endocytosis is involved in DNA uptake in yeast. Biochim Biophys Acta 1572(1):67-76 {{SGDpaper|S000070388}} PMID 12204334</ref><ref name='S000075100'>Sickmann A, et al. (2003) The proteome of Saccharomyces cerevisiae mitochondria. Proc Natl Acad Sci U S A 100(23):13207-12 {{SGDpaper|S000075100}} PMID 14576278</ref><ref name='S000042833'>Singer-Kruger B, et al. (1994) Role of three rab5-like GTPases, Ypt51p, Ypt52p, and Ypt53p, in the endocytic and vacuolar protein sorting pathways of yeast. J Cell Biol 125(2):283-98 |
{{SGDpaper|S000042833}} PMID 8163546</ref> | {{SGDpaper|S000042833}} PMID 8163546</ref> | ||
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Revision as of 14:05, 14 May 2010
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Systematic name | YOR089C |
Gene name | VPS21 |
Aliases | VPS12, VPT12, YPT21, YPT51 |
Feature type | ORF, Verified |
Coordinates | Chr XV:490830..490198 |
Primary SGDID | S000005615 |
Description of YOR089C: Rab family GTPase required for endocytic transport and for sorting of vacuolar hydrolases; localized in endocytic intermediates; detected in mitochondria; geranylgeranylation required for membrane association; mammalian Rab5 homolog[1][2][3][4]
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References
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- ↑ Horazdovsky BF, et al. (1994) VPS21 encodes a rab5-like GTP binding protein that is required for the sorting of yeast vacuolar proteins. EMBO J 13(6):1297-309 SGD PMID 8137814
- ↑ Neukamm B, et al. (2002) Endocytosis is involved in DNA uptake in yeast. Biochim Biophys Acta 1572(1):67-76 SGD PMID 12204334
- ↑ Sickmann A, et al. (2003) The proteome of Saccharomyces cerevisiae mitochondria. Proc Natl Acad Sci U S A 100(23):13207-12 SGD PMID 14576278
- ↑ Singer-Kruger B, et al. (1994) Role of three rab5-like GTPases, Ypt51p, Ypt52p, and Ypt53p, in the endocytic and vacuolar protein sorting pathways of yeast. J Cell Biol 125(2):283-98 SGD PMID 8163546
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