Difference between revisions of "YDR496C"
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| − | '''Description of YDR496C:''' Pumilio-homology domain protein that binds | + | '''Description of YDR496C:''' Pumilio-homology domain protein that binds the 3' UTR of ASH1 mRNA and represses its translation, resulting in proper asymmetric localization of ASH1 mRNA; also co-sediments with the 60S ribosomal subunit and is required for its biogenesis<ref name='S000076338'>Gu W, et al. (2004) A new yeast PUF family protein, Puf6p, represses ASH1 mRNA translation and is required for its localization. Genes Dev 18(12):1452-65 {{SGDpaper|S000076338}} PMID 15198983</ref><ref name='S000131880'>Li Z, et al. (2009) Rational extension of the ribosome biogenesis pathway using network-guided genetics. PLoS Biol 7(10):e1000213 |
| − | {{SGDpaper| | + | {{SGDpaper|S000131880}} PMID 19806183</ref> |
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Revision as of 13:05, 3 May 2010
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| Systematic name | YDR496C |
| Gene name | PUF6 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:1443396..1441426 |
| Primary SGDID | S000002904 |
Description of YDR496C: Pumilio-homology domain protein that binds the 3' UTR of ASH1 mRNA and represses its translation, resulting in proper asymmetric localization of ASH1 mRNA; also co-sediments with the 60S ribosomal subunit and is required for its biogenesis[1][2]
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References
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- ↑ Gu W, et al. (2004) A new yeast PUF family protein, Puf6p, represses ASH1 mRNA translation and is required for its localization. Genes Dev 18(12):1452-65 SGD PMID 15198983
- ↑ Li Z, et al. (2009) Rational extension of the ribosome biogenesis pathway using network-guided genetics. PLoS Biol 7(10):e1000213 SGD PMID 19806183
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