Difference between revisions of "YEL013W"
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==Community Commentary== | ==Community Commentary== |
Revision as of 11:51, 24 January 2007
Share your knowledge...Edit this entry!
Systematic name | YEL013W | |
Gene name | VAC8 | |
Aliases | YEB3 | |
Feature type | ORF, Verified | |
Coordinates | Chr V:128825..130561 | |
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Description of YEL013W: Phosphorylated vacuolar membrane protein that interacts with Atg13p, required for the cytoplasm-to-vacuole targeting (Cvt) pathway; interacts with Nvj1p to form nucleus-vacuole junctions[1][2][3]
Community Commentary
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Interactions
Physical
Physical interaction with VAC17
Immunoprecipitating Vac17p with sheep anti-Vac17p antibody coprecipitates Vac8p. [4] [5]
Two Hybrid
Two Hybrid interaction with VAC17
Residues 290-380 of Vac17p interact with Vac8p in a yeast two-hybrid analysis. [4] [5]
References
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- ↑ Wang YX, et al. (1998) Vac8p, a vacuolar protein with armadillo repeats, functions in both vacuole inheritance and protein targeting from the cytoplasm to vacuole. J Cell Biol 140(5):1063-74 SGD PMID 9490720
- ↑ Scott SV, et al. (2000) Apg13p and Vac8p are part of a complex of phosphoproteins that are required for cytoplasm to vacuole targeting. J Biol Chem 275(33):25840-9 SGD PMID 10837477
- ↑ Pan X, et al. (2000) Nucleus-vacuole junctions in Saccharomyces cerevisiae are formed through the direct interaction of Vac8p with Nvj1p. Mol Biol Cell 11(7):2445-57 SGD PMID 10888680
- ↑ 4.0 4.1 Tang F, et al. (2003) Regulated degradation of a class V myosin receptor directs movement of the yeast vacuole. Nature 422(6927):87-92 SGD PMID 12594460
- ↑ 5.0 5.1 submitted by Fusheng Tang on 2003-03-17
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