Difference between revisions of "YNL230C"
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| − | '''Description of YNL230C:''' Elongin A, F-box protein that forms a heterodimer with Elc1p and is required for ubiquitin-dependent degredation of the RNA Polymerase II subunit RPO21; subunit of the Elongin-Cullin-Socs (ECS) ligase complex<ref name='S000040848'>Botuyan MV, et al. (1999) Binding of elongin A or a von Hippel-Lindau peptide stabilizes the structure of yeast elongin C. Proc Natl Acad Sci U S A 96(16):9033-8 {{SGDpaper|S000040848}} PMID 10430890</ref><ref name='S000120848'>Ribar B, et al. (2007) ELA1 and CUL3 are required along with ELC1 for RNA polymerase II polyubiquitylation and degradation in DNA-damaged yeast cells. Mol Cell Biol 27(8):3211-6 {{SGDpaper|S000120848}} PMID 17296727 | + | '''Description of YNL230C:''' Elongin A, F-box protein that forms a heterodimer with Elc1p and is required for ubiquitin-dependent degredation of the RNA Polymerase II subunit RPO21; subunit of the Elongin-Cullin-Socs (ECS) ligase complex<ref name='S000040848'>Botuyan MV, et al. (1999) Binding of elongin A or a von Hippel-Lindau peptide stabilizes the structure of yeast elongin C. Proc Natl Acad Sci U S A 96(16):9033-8 {{SGDpaper|S000040848}} PMID 10430890</ref><ref name='S000122537'>Gillette TG, et al. (2006) Distinct functions of the ubiquitin-proteasome pathway influence nucleotide excision repair. EMBO J 25(11):2529-38 {{SGDpaper|S000122537}} PMID 16675952</ref><ref name='S000120848'>Ribar B, et al. (2007) ELA1 and CUL3 are required along with ELC1 for RNA polymerase II polyubiquitylation and degradation in DNA-damaged yeast cells. Mol Cell Biol 27(8):3211-6 |
| − | + | {{SGDpaper|S000120848}} PMID 17296727</ref> | |
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Revision as of 13:05, 25 February 2010
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| Systematic name | YNL230C |
| Gene name | ELA1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XIV:218663..217524 |
| Primary SGDID | S000005174 |
Description of YNL230C: Elongin A, F-box protein that forms a heterodimer with Elc1p and is required for ubiquitin-dependent degredation of the RNA Polymerase II subunit RPO21; subunit of the Elongin-Cullin-Socs (ECS) ligase complex[1][2][3]
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References
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- ↑ Botuyan MV, et al. (1999) Binding of elongin A or a von Hippel-Lindau peptide stabilizes the structure of yeast elongin C. Proc Natl Acad Sci U S A 96(16):9033-8 SGD PMID 10430890
- ↑ Gillette TG, et al. (2006) Distinct functions of the ubiquitin-proteasome pathway influence nucleotide excision repair. EMBO J 25(11):2529-38 SGD PMID 16675952
- ↑ Ribar B, et al. (2007) ELA1 and CUL3 are required along with ELC1 for RNA polymerase II polyubiquitylation and degradation in DNA-damaged yeast cells. Mol Cell Biol 27(8):3211-6 SGD PMID 17296727
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