Difference between revisions of "YNL119W"

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'''Description of YNL119W:''' Protein required for thiolation of the uridine at the wobble position of Lys(UUU) and Glu(UUC) tRNAs; has a role in urmylation and in invasive and pseudohyphal growth; inhibits replication of Brome mosaic virus in S. cerevisiae<ref name='S000076816'>Kushner DB, et al. (2003) Systematic, genome-wide identification of host genes affecting replication of a positive-strand RNA virus. Proc Natl Acad Sci U S A 100(26):15764-9 {{SGDpaper|S000076816}} PMID 14671320</ref><ref name='S000075061'>Goehring AS, et al. (2003) Urmylation: a ubiquitin-like pathway that functions during invasive growth and budding in yeast. Mol Biol Cell 14(11):4329-41 {{SGDpaper|S000075061}} PMID 14551258</ref><ref name='S000127266'>Nakai Y, et al. (2008) Thio-modification of Yeast Cytosolic tRNA Requires a Ubiquitin-related System That Resembles Bacterial Sulfur Transfer Systems. J Biol Chem 283(41):27469-76
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'''Description of YNL119W:''' Protein required for thiolation of the uridine at the wobble position of Lys(UUU) and Glu(UUC) tRNAs; has a role in urmylation and in invasive and pseudohyphal growth; inhibits replication of Brome mosaic virus in S. cerevisiae<ref name='S000075061'>Goehring AS, et al. (2003) Urmylation: a ubiquitin-like pathway that functions during invasive growth and budding in yeast. Mol Biol Cell 14(11):4329-41 {{SGDpaper|S000075061}} PMID 14551258</ref><ref name='S000076816'>Kushner DB, et al. (2003) Systematic, genome-wide identification of host genes affecting replication of a positive-strand RNA virus. Proc Natl Acad Sci U S A 100(26):15764-9 {{SGDpaper|S000076816}} PMID 14671320</ref><ref name='S000127266'>Nakai Y, et al. (2008) Thio-modification of Yeast Cytosolic tRNA Requires a Ubiquitin-related System That Resembles Bacterial Sulfur Transfer Systems. J Biol Chem 283(41):27469-76
 
  {{SGDpaper|S000127266}} PMID 18664566</ref>
 
  {{SGDpaper|S000127266}} PMID 18664566</ref>
 
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Revision as of 13:05, 25 February 2010

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Systematic name YNL119W
Gene name NCS2
Aliases TUC2
Feature type ORF, Verified
Coordinates Chr XIV:401042..402523
Primary SGDID S000005063


Description of YNL119W: Protein required for thiolation of the uridine at the wobble position of Lys(UUU) and Glu(UUC) tRNAs; has a role in urmylation and in invasive and pseudohyphal growth; inhibits replication of Brome mosaic virus in S. cerevisiae[1][2][3]




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References

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  1. Goehring AS, et al. (2003) Urmylation: a ubiquitin-like pathway that functions during invasive growth and budding in yeast. Mol Biol Cell 14(11):4329-41 SGD PMID 14551258
  2. Kushner DB, et al. (2003) Systematic, genome-wide identification of host genes affecting replication of a positive-strand RNA virus. Proc Natl Acad Sci U S A 100(26):15764-9 SGD PMID 14671320
  3. Nakai Y, et al. (2008) Thio-modification of Yeast Cytosolic tRNA Requires a Ubiquitin-related System That Resembles Bacterial Sulfur Transfer Systems. J Biol Chem 283(41):27469-76 SGD PMID 18664566

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