Difference between revisions of "YNL116W"

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'''Description of YNL116W:''' Protein involved in ubiquitination; plays a role in regulating spindle position and orientation; functionally redundant with Dma1p; orthologous to human RNF8 protein, also has sequence similarity to human Chfr<ref name='S000077036'>Fraschini R, et al. (2004) Functional characterization of Dma1 and Dma2, the budding yeast homologues of Schizosaccharomyces pombe Dma1 and human Chfr. Mol Biol Cell 15(8):3796-810 {{SGDpaper|S000077036}} PMID 15146058</ref><ref name='S000125080'>Tuttle RL, et al. (2007) Defective in mitotic arrest 1/ring finger 8 is a checkpoint protein that antagonizes the human mitotic exit network. Mol Cancer Res 5(12):1304-11 {{SGDpaper|S000125080}} PMID 18171988</ref><ref name='S000125264'>Loring GL, et al. (2008) Yeast Chfr homologs retard cell cycle at G1 and G2/M via Ubc4 and Ubc13/Mms2-dependent ubiquitination. Cell Cycle 7(1):96-105
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'''Description of YNL116W:''' Protein involved in ubiquitination; plays a role in regulating spindle position and orientation; functionally redundant with Dma1p; orthologous to human RNF8 protein, also has sequence similarity to human Chfr<ref name='S000077036'>Fraschini R, et al. (2004) Functional characterization of Dma1 and Dma2, the budding yeast homologues of Schizosaccharomyces pombe Dma1 and human Chfr. Mol Biol Cell 15(8):3796-810 {{SGDpaper|S000077036}} PMID 15146058</ref><ref name='S000125264'>Loring GL, et al. (2008) Yeast Chfr homologs retard cell cycle at G1 and G2/M via Ubc4 and Ubc13/Mms2-dependent ubiquitination. Cell Cycle 7(1):96-105 {{SGDpaper|S000125264}} PMID 18202552</ref><ref name='S000125080'>Tuttle RL, et al. (2007) Defective in mitotic arrest 1/ring finger 8 is a checkpoint protein that antagonizes the human mitotic exit network. Mol Cancer Res 5(12):1304-11
{{SGDpaper|S000125264}} PMID 18202552</ref>
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{{SGDpaper|S000125080}} PMID 18171988</ref>
 
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Revision as of 14:05, 25 February 2010

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Systematic name YNL116W
Gene name DMA2
Aliases CHF2
Feature type ORF, Verified
Coordinates Chr XIV:408343..409911
Primary SGDID S000005060


Description of YNL116W: Protein involved in ubiquitination; plays a role in regulating spindle position and orientation; functionally redundant with Dma1p; orthologous to human RNF8 protein, also has sequence similarity to human Chfr[1][2][3]




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References

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  1. Fraschini R, et al. (2004) Functional characterization of Dma1 and Dma2, the budding yeast homologues of Schizosaccharomyces pombe Dma1 and human Chfr. Mol Biol Cell 15(8):3796-810 SGD PMID 15146058
  2. Loring GL, et al. (2008) Yeast Chfr homologs retard cell cycle at G1 and G2/M via Ubc4 and Ubc13/Mms2-dependent ubiquitination. Cell Cycle 7(1):96-105 SGD PMID 18202552
  3. Tuttle RL, et al. (2007) Defective in mitotic arrest 1/ring finger 8 is a checkpoint protein that antagonizes the human mitotic exit network. Mol Cancer Res 5(12):1304-11 SGD PMID 18171988

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