Difference between revisions of "YJR078W"
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− | '''Description of YJR078W:''' Putative tryptophan 2,3-dioxygenase or indoleamine 2,3-dioxygenase, required for the de novo biosynthesis of NAD from tryptophan via kynurenine; expresssion is upregulated upon telomere uncapping; regulated by Hst1p and Aft2p<ref name=' | + | '''Description of YJR078W:''' Putative tryptophan 2,3-dioxygenase or indoleamine 2,3-dioxygenase, required for the de novo biosynthesis of NAD from tryptophan via kynurenine; expresssion is upregulated upon telomere uncapping; regulated by Hst1p and Aft2p<ref name='S000074280'>Bedalov A, et al. (2003) NAD+-dependent deacetylase Hst1p controls biosynthesis and cellular NAD+ levels in Saccharomyces cerevisiae. Mol Cell Biol 23(19):7044-54 {{SGDpaper|S000074280}} PMID 12972620</ref><ref name='S000127932'>Greenall A, et al. (2008) A genome wide analysis of the response to uncapped telomeres in budding yeast reveals a novel role for the NAD+ biosynthetic gene BNA2 in chromosome end protection. Genome Biol 9(10):R146 {{SGDpaper|S000127932}} PMID 18828915</ref><ref name='S000069977'>Panozzo C, et al. (2002) Aerobic and anaerobic NAD+ metabolism in Saccharomyces cerevisiae. FEBS Lett 517(1-3):97-102 {{SGDpaper|S000069977}} PMID 12062417</ref><ref name='S000073710'>Rutherford JC, et al. (2003) Aft1p and Aft2p mediate iron-responsive gene expression in yeast through related promoter elements. J Biol Chem 278(30):27636-43 {{SGDpaper|S000073710}} PMID 12756250</ref><ref name='S000125783'>Yuasa HJ, et al. (2007) Evolution of vertebrate indoleamine 2,3-dioxygenases. J Mol Evol 65(6):705-14 |
− | {{SGDpaper| | + | {{SGDpaper|S000125783}} PMID 18026683</ref> |
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Revision as of 13:05, 25 February 2010
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Systematic name | YJR078W |
Gene name | BNA2 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr X:578852..580213 |
Primary SGDID | S000003839 |
Description of YJR078W: Putative tryptophan 2,3-dioxygenase or indoleamine 2,3-dioxygenase, required for the de novo biosynthesis of NAD from tryptophan via kynurenine; expresssion is upregulated upon telomere uncapping; regulated by Hst1p and Aft2p[1][2][3][4][5]
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References
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- ↑ Bedalov A, et al. (2003) NAD+-dependent deacetylase Hst1p controls biosynthesis and cellular NAD+ levels in Saccharomyces cerevisiae. Mol Cell Biol 23(19):7044-54 SGD PMID 12972620
- ↑ Greenall A, et al. (2008) A genome wide analysis of the response to uncapped telomeres in budding yeast reveals a novel role for the NAD+ biosynthetic gene BNA2 in chromosome end protection. Genome Biol 9(10):R146 SGD PMID 18828915
- ↑ Panozzo C, et al. (2002) Aerobic and anaerobic NAD+ metabolism in Saccharomyces cerevisiae. FEBS Lett 517(1-3):97-102 SGD PMID 12062417
- ↑ Rutherford JC, et al. (2003) Aft1p and Aft2p mediate iron-responsive gene expression in yeast through related promoter elements. J Biol Chem 278(30):27636-43 SGD PMID 12756250
- ↑ Yuasa HJ, et al. (2007) Evolution of vertebrate indoleamine 2,3-dioxygenases. J Mol Evol 65(6):705-14 SGD PMID 18026683
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